Virus-driven genome engineering causes cancer?

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Inhibition of p53 prevents the damage response and increases the rate of homologous recombination… In the 1990’s, Abcam researchers discovered the cell death gene. Now see: Mechanisms of Recombination conference See also: P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells We demonstrated the toxic response is tp53-dependent and the toxic effect of tp53 severely reduces the efficiency of precise genome-engineering in hPSCs. Reported as:…

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2018 March for Science vs microRNAs

Summary: Only biologically uninformed theorists and other pseudoscientists do not seem to know that all carbon-based life is quantized energy-dependent and that biophotonic energy as information comes from the sun. It is obvious to all serious scientists that proton gradients link photons from quantized energy as information to the proton motive force, which is how the potential of hydrogen (pH) is linked to changes in the microRNA/messenger RNA balance that biophysically constrain viral latency in the context of hydrogen-atom transfer…

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The eternal significance of microRNAs (2)

Summary: What is known for sure, however, is that biological processes called “nature” are not simplistic. Neither is the entity called “the environment.” The two separate worlds overlap and intertwine so only a single interactive one exists. Yes, it may be simpler to look at each singly, but one does so at intellectual peril. The Immune Landscape of Cancer (2018) Multiple control modalities of the intracellular and extracellular networks (transcription, microRNAs, copy number, and epigenetic processes) were involved in tumor-immune…

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Death cures theorist’s Amyotrophic Lateral Sclerosis (ALS).

Stephen Hawking death: Was he the smartest man in the world? The media need superheroes in science just as in every sphere of life, but there is really a continuous range of abilities with no clear dividing line. For comparison: Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS) A pathogenic mutation in D-amino acid oxidase (DAO) associated with familial ALS impairs D-serine metabolism and causes protein aggregation, autophagy and cell death…

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Diet-driven RNA interference and mental health (2)

The diet-driven construction of the competing endogenous RNA networks (ceRNA networks) is energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction. Viruses compete for the energy, which is how they contribute to the degradation of messenger RNA that all serious scientists have linked to all mental and physical pathology. Cell death is not just seen in the context of autophagy and neural cell death. The pathogens that alter physiology also alter behavior via the conserved molecular mechanisms of energy-dependent…

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For God and Country

Diet-driven RNA interference and cancer prevention (4)

Excerpt: What I perceive as apathy can be attributed to the lack of empathy for anyone who suffers from the preventable or controlled virus-driven pathology that, sooner or later, kills us all. In the case of our Vietnam veterans, naturally occurring prevention or effective treatment of glioblastoma might be achieved by dietary intervention with a curcumin supplement. “micrornas”[MeSH Terms] OR “micrornas”[All Fields] OR “microrna”[All Fields] Items: 1 to 20 of 68871 See:  The tipping point (revisited): 68,000 publications 69,000 published…

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Quantized energy-dependent viral trophism

…mutations cause activation of your death gene. Conclusion: You may be able to stop the ongoing activation of your death gene by a change in diet. See: Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene See also: A Concise Review of MicroRNA Exploring the Insights of MicroRNA Regulations in Bacterial, Viral and Metabolic Diseases ——————————————– Daniel L.Hurdiss (@DanielHurdiss) announced publication of this refutation of neo-Darwinian pseudoscientific nonsense in his twitter feed before the…

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Lethal virus kills 5 billion people?

Reporting new scientific truths is not allowed in the USA

Summary: If we keep training serious scientists in the United States but force them to return to their homeland to report new scientific truths, our Homeland Security will suffer from the ignorance of pseudoscientists who are still touting ridiculous claims about mutations and evolution. A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die, and a new generation grows up that is familiar with it. Every…

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Energy-dependent physical and biophysical constraints (7)

See first: Energy-dependent physical and biophysical constraints (6) Stems Cells in the Hypothalamus Slow Aging in Mice My comment to The Scientist Cai says microRNAs could be a potential mechanism by which hypothalamic neural stem cells have such wide-ranging effects on aging, yet he believes that neurogenesis may also be involved. See also: Feedback loops link odor and pheromone signaling with reproduction At least 10,000 neurons in 26 different brain areas appear to transmit signals directly to GnRH neurons.  GnRH…

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