glycolysis

Predicting who wins the 2017 Nobel Prizes (7)

Conclusion: The biggest threat to humanity is not the “Big Bang” theory of creation or the “Big Bang” theory of how life on Earth might end after an explosion of cosmic proportions. The biggest threat has always been “human idiocy.” 2017 Nobel Peace Prize Awarded to International Campaign to Abolish Nuclear Weapons “for its work to draw attention to the catastrophic humanitarian consequences of any use of nuclear weapons and for its ground-breaking efforts to achieve a treaty-based prohibition of…

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From E. coli to monkeys and mankind: Theories vs models (2)

Dedicated to Dr. Tom Jordan and Priscilla Jordan on the day of their retirement from the Baptist ministry, May 28, 2017. They always encouraged me to learn more about the “Laws of Biology” and link the Laws from energy as information to all biodiversity on Earth via the physiology of reproduction. See also: From E. coli to monkeys and mankind: Theories vs models High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding (5/23/127) …changes in observed association…

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Energy-dependent microRNA biogenesis

Published May 3, 2017 Genetic variation and RNA structure regulate microRNA biogenesis …primary sequence determinants and RNA structure are key regulators of miRNA biogenesis. Genetic variation aka primary sequence determinants are energy-dependent and RNA-mediated. Energy-dependent RNA methylation is an experience-dependent link from natural selection for energy-dependent codon optimality. Natural selection for energy-dependent codon optimality links ATP-dependent microRNA biogenesis to RNA biosynthesis. Ridiculous attempts to portray energy-dependent top-down causation as if genetic variation came first may continue for another 52 years.…

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Cytosis: Biology Content

  Help Me Write Some Biology Content Project Update #5: Cytosis: A Cell Biology Board Game by John Coveyou (Genius Games) Many of you have mentioned that you’d like to have an explanation of the biology behind Cytosis available… and I think that is an AWESOME plan. Every time I’ve taught the game to non-science players in the past, they say gameplay made even more sense (and was so much more enjoyable) when I explained the science as well. This…

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Mitochondria do not adapt

Mitochondria Help Cancers Grow Mitochondria adapt by producing cycles whereby electrons are removed from carbon at a greater rate as food is oxidized to make molecules for the cancers. Mitochondria do not ‘produce’ the ‘cycles’ that link ‘food’ from one carbon metabolism to healthy longevity. Mitochondria do not ‘adapt.’ The food enables thermodynamic cycles of nutrient energy-dependent protein biosynthesis and degradation. Jon Lieff’s “doublespeak” obscures, disguises, distorts, or reverses the meaning of words. See also his section about: Altering Amino…

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From angstroms to ecosystems and entropy

Text with these references to follow. The two submissions should be available within the month. I will announce the availability and add the text with links to the citations at that time. From hydrogen-atom transfer in DNA base pairs to ecosystems [1] Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system [2] Ultraviolet Absorption Induces Hydrogen-Atom Transfer in G⋅C Watson–Crick DNA Base Pairs in Solution. [3] Photonic Maxwell’s Demon [4] Common origins of RNA, protein and lipid…

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Nutrient-dependent RNA-mediated cause and effect

Could the food we eat affect our genes? Study in yeast suggests this may be the case (2016) Excerpt: “Cellular metabolism plays a far more dynamic role in the cells than we previously thought,” explains Dr Ralser. “Nearly all of a cell’s genes are influenced by changes to the nutrients they have access to. In fact, in many cases the effects were so strong, that changing a cell’s metabolic profile could make some of its genes behave in a completely…

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