GnRH

RNA-directed gene choice

March 17, 2015
James Kohl
Adaptations, Ecology, Human Pheromones, Model Organisms, Physics, RNA Directed
No Comments

March 2015: ChemoSense; see Timothy S. McClintock: “Odorant Receptor Gene Choice” He concludes: “The epigenetic control of OR gene expression through repression and de-repression is a remarkable story, and as a fundamental mechanism intimately associated with the random differentiation of a neural progenitor cell into multiple neuronal subtypes, one wonders whether it might be a framework for understanding other instances of differentiation of neural subtypes (Lyons and Lomvardas, 2014).” My comment: The epigenetic control of OR gene expression is RNA-directed…

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Quantum Superpositions: let there be light

January 29, 2015
James Kohl
Ecology, Physics
No Comments

Ideal Negative Measurements in Quantum Walks Disprove Theories Based on Classical Trajectories Reported as: Atoms can be in two places at the same time Excerpt: “This is not yet a proof that quantum mechanics hold for large objects,” cautions Alberti. My comment: I framed my comments and a question in the context of this article on physics. Their claim of a possible size limit on quantum superpositions seemed to divorce top-down causation from cell–cell communication in mammals. That suggested there…

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Model organisms: the birds and the bees

December 12, 2014
James Kohl
Adaptations, Ecology, Human Pheromones, Model Organisms, Variations
No Comments

Bird Genomes Abound Scientists complete the largest-ever comparative genomic study of birds. By Ruth Williams | December 11, 2014 Excerpt: “Birds are model organisms for a number of human behaviors and conditions—For example, Jarvis compares vocal learning in birds and humans—so determining the genetic basis of such traits requires genetic history.” My comment: Honeybees are model organisms for “…human immunity, disease resistance, allergic reaction, circadian rhythms, antibiotic resistance, the development of the brain and behavior, mental health, longevity, diseases of…

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Chemical ecology and RNA-mediated control of DNA loops

December 12, 2014
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms
No Comments

DNA Loop-the-Loops A new full-genome map indicates how DNA is folded within the nuclei of human cells.By Kate Yandell | December 11, 2014 Excerpt: “…many loops were conserved among cell types, and even between mice and humans. But others seemed to drive cell type-specific gene expression patterns.” My comment to The Scientist Magazine: Nutrient-dependent/pheromone-controlled adaptive evolution: a model. Excerpt: “A form of GnRH associated with sexual orientation in yeasts links control of the feedback loops and developmental processes required for…

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Atoms to ecosystems: Evolutionary theory vs the coelacanth

December 11, 2014
James Kohl
Adaptations, Ecology, Human Pheromones, Model Organisms
No Comments

Biodiversity: Life ­– a status report “Species are disappearing quickly — but researchers are struggling to assess how bad the problem is.” I want to eliminate some of the researcher’s struggles, but a moderator at Nature has blocked all my comments for several months, perhaps permanently. I think my past comments on articles, like this one, explain why other comments are blocked. In the past, I commented each time I saw a misrepresentation of biologically-based cause and effect. The misrepresentations…

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Jumping back: Science or Pseudoscience?

December 5, 2014
James Kohl
Ecology
One Comment

Daily Comment November 21, 2014 European Science’s Great Leap Backward By Michael Specter Excerpt 1) “When politicians reject verifiable data and reputable research and rely instead on politics or desire, the results can be devastating.” Excerpt 2 with my emphasis) “…scientific organizations from around the world… have strongly endorsed the safety of G.M. foods. (It should be noted that the U.S. can claim no superiority in our approach to evidence-based science, as demonstrated by the fact that nearly half of…

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Glycine and GnRH: Am I being pedantic?

December 4, 2014
James Kohl
Diseases & Disorders, Ecology, Model Organisms
No Comments

Posted to the FB page on 12/3/14 at Skeptics; Atheists; Realists; Agnostics; Humanists Stephen Hawking and Brian Cox take part in Monty Python sketch – video Excerpt: “I think you are being pedantic.” My comment: Some people may think I am being pedantic. My focus is not on physics; it is on the role of GnRH in cell type differentiation. My focus now extends from what is known about quantum physics, quantum smell, chirality, quantum biology, and quantum consciousness. What is known about chirality…

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Sackler Colloquium: Effects or AFFECTS on Behavior

November 19, 2014
James Kohl
Adaptations, Ecology, Human Brain, Model Organisms, Variations
No Comments

Arthur M. Sackler Colloquium of the National Academy of Sciences, “Epigenetic Changes in the Developing Brain: Effects on Behavior,” held March 28–29, 2014, at the National Academy of Sciences in Washington, DC. The complete program and video recordings of most presentations are available on the NAS website. I reiterate: the title is: Epigenetic changes in the developing brain: Effects on behavior I was taught that the epigenetic landscape must be linked to physical landscape of DNA in organized genomes of…

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There’s a model for that!

November 12, 2014
James Kohl
Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms
No Comments

Neuroscientists reveal mechanism crucial to molding male brains Excerpt 1) “…sex differences in brain function are established during the later stages of foetal development and around birth, but the actual cellular mechanisms underlying these important actions remained unknown.” My comment: In our 1996 Hormones and Behavior review we provided details about how these cellular mechanisms link sex differences in brain function, which are established during the later stages of fetal development, to the sex differences that are established perinatally. We…

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Biologists puzzled by evolved RNAs and decaying DNA

November 11, 2014
James Kohl
Diseases & Disorders, Ecology
No Comments

Horizontal Transfer of Entire Genomes via Mitochondrial Fusion in the Angiosperm Amborella (December, 2013) Excerpt) “The ancestral angiosperm-wide genome duplication apparent in the Amborella genome not only serves as a genetic marker for the origin of extant angiosperms, but it may also have set in motion a series of events as numerous genes evolved novel functions, eventually leading to modern flowering plants.” See also: The Amborella Genome and the Evolution of Flowering Plants Excerpt) “Evolution of Small RNAs More than…

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