hydrogen-atom transfer in DNA base pairs in solution Archives - Page 9 of 9

Jay R. Feierman: twenty years of antagonism

March 11, 2016

Adaptations, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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Jay R. Feierman began his antagonism when we first met. At a poster presentation during a prestigious conference in 1995, I detailed all the aspects of my mammalian model. He asked “What about birds?” He is the”bird-watching” moderator of the International Society for Human Ethology (ISHE) yahoo group who banned me from participation last year when I failed to answer a “yes” or “no” question about the role of RNA in cell type differentiation. Since then, his attacks on my…

Do not miss the misrepresentations

March 8, 2016

James Kohl

Adaptations, Diseases & Disorders, Ecology, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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PLOS Biology ICYMI: February’s Five January 25, 2016 Reported as 1) “… they hypothesise short bursts of rapid species diversification, such as after the famous mass extinction event…” January 11, 2016 Reported as 2) “…a newly identified protein, Wuho (WH), regulates the activity of FEN1 when around a replication fork, ensuring it does more good acting as a flap endonuclease than damage as a gap endonuclease.” January 7, 2016 Reported as 3) “Exosomes Protect and Perpetuate Chemical Attractants” February 12,…

Energy dependent RNA-mediated immunity (3)

March 5, 2016

James Kohl

Adaptations, Diseases & Disorders, Ecology, Human Brain, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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Viral ‘fossils’ in our DNA may help us fight infection Excerpt: The work suggests that these viral fossils probably played a key role in the evolution of our species… My comment: The work shows that Greg Bear accurately portrayed virus-driven energy theft when he linked it to the creation of new species. In 1999 and 2003, he linked what is now known about the anti-entropic effects of sunlight and hydrogen-energy transfer in DNA base pairs in solution to the creation…

RNA-mediated DNA modifications

March 1, 2016

James Kohl

Adaptations, Ecology, RNA Directed

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A new way to discover DNA modifications Excerpt: Using their approach, which combines bioanalytical chemistry, comparative genomics, and a special type of DNA sequencing, the team has discovered a DNA modification that helps bacteria to protect their genomes from viral infection. My comment: There is one way to link nutrient-dependent microRNA flanking sequences from adhesion proteins to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. It starts with energy-dependent changes in hydrogen-atom transfer in…

Science vs semantics

February 25, 2016

James Kohl

Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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Re-interpreting long-term evolution experiments — Is delayed adaptation an example of historical contingency or a consequence of intermittent selection? Excerpt: “… the series of events used to explain adaptation in the short-transfer LTEE (and in speciation) might need to be revised. The amplification model supported by this article has already be proposed as a means of evolving new genes (1) and has been experimentally shown capable of generating a novel genetic function within as few as 3000 cell generations (11).…

Bacteria see the light and they adapt (2)

February 22, 2016

James Kohl

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Differential Odour Coding of Isotopomers in the Honeybee Brain Conclusion: In summary, we provided the first neurophysiological evidence of differential neural coding of isotopomers. Also, in light of the recent literature on ODEs, and considering that odour transduction in insects occurs in ≈2 ms24, it seems unlikely that perireceptor events could be responsible for the reported isotope sensitivity. Finally, we performed direct measurements of the vibrational spectra of each odorant, and reported that spectral differences among isotopomers well reflect differences in…

Bringing RNA back to epigenetics (20 years later)

February 19, 2016

James Kohl

Adaptations, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, Variations

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Has Contemporary Academia Outgrown the Carl Sagan Effect? [Subscription required] Excerpt (with my emphasis): [Sean Carroll] offered 13 pieces of advice…: “Do good research; Make an impact in the field; Bring in grant money… Don’t be too well known outside the field; Don’t write a book; Choose your hobbies wisely.” Carroll argued that academics look askance at colleagues that have too high of a public profile. Not out of envy—but because they worry that public scientists care more about their…

Hybrids: making microbes and Democrats into monkey’s uncles?

February 16, 2016

James Kohl

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Darwinists Underestimate Nature. Creationists Underestimate God. Excerpt: Doug, here’s what we know: Two processes produce new species in real time – 1) Hybrids, where Species 1 crossed with Species 2 gives you Species 3. Example: Emmer wheats + goat grass = modern wheat. This doubles the number of chromosomes. After this merger, “hybrid dysgenesis” kicks in. Extensive genome editing re-arranges and deletes parts of the new DNA. Genome studies indicate that a hybridization event of this kind got us from…