hypothalamus Archives | RNA-Mediated

Energy-dependent physical and biophysical constraints (8)

July 27, 2017

Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations

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Summary: The role of vitamin C in the treatment of pain: new insights links what is known about the “superfood” Spirulina (blue-green algae), which is grown in marine and freshwater environments, to the stability of all organized genomes via its biological activities, such as antioxidant, anti-diabetic, cholesterol-controlling and insulin resistance effects. The biological activities are energy-dependent and they link the anti-entropic virucidal energy of sunlight to all biodiversity via the pheromone-controlled physiology of reproduction and microRNAs in plants and animals.…

Energy-dependent physical and biophysical constraints (7)

July 27, 2017

James Kohl

Adaptations, Ecology, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations

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See first: Energy-dependent physical and biophysical constraints (6) Stems Cells in the Hypothalamus Slow Aging in Mice My comment to The Scientist Cai says microRNAs could be a potential mechanism by which hypothalamic neural stem cells have such wide-ranging effects on aging, yet he believes that neurogenesis may also be involved. See also: Feedback loops link odor and pheromone signaling with reproduction At least 10,000 neurons in 26 different brain areas appear to transmit signals directly to GnRH neurons. GnRH…

Thermotolerance and longevity (2)

June 1, 2016

James Kohl

Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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See also: Thermotolerance and Longevity This article is part of the Research Topic Brain nutrient sensing in the control of energy balance: new insights and perspectives Excerpt: It is well established that nutrients act as signaling molecules in synergy with nervous and hormonal signals to inform the brain about the nutritional status of the body. The integration of these signals within the hypothalamus and other brain regions triggers behavioral and physiological responses through efferent autonomic nerves, hypothalamic-pituitary-Adrenal and thyroid axis…

The miRNA/mRNA balance: a suboptimal strategy?

April 6, 2015

James Kohl

Adaptations, Ecology, Model Organisms

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Cells exercise suboptimal strategy to survive Excerpt: “Learning the secrets of alternate molecular pathways could provide clues about how to use them to patients’ advantage, she said.” My comment: The same molecular pathways control the nutrient-dependent physiology of reproduction in all genera. They link RNA-directed DNA methylation to RNA-mediated cell type differentiation via fixation of amino acid substitutions that determine cell types. See also: Epistasis Among Adaptive Mutations in Deer Mouse Hemoglobin “Mechanisms of epistasis are often best revealed through…

Achiral GnRH: no prophesy, just prediction

November 8, 2014

James Kohl

Diseases & Disorders, Ecology

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Predictions build on facts, mysterious “tongues” do not. (1 Corinthians 14:2-4) Effective communication demands that audiences understand what serious scientists and theologians can or cannot predict. Predicting the end of evolutionary theory or the end of the world by focusing on a model of biological facts may be an important aspect of effective communication. A problem may be the words and phrases that pseudoscientists and serious scientists use. Some make biological facts seem like mysteries until the facts are effectively…