inflammation

From base editing to RNA editing (8)

Excerpt: See: Quantum Vacuum Dynamics, Coherence, Superluminal Photons and Hypercomputation in Brain Microtubules Finally, these theorists attempt to link the speed of light on contact with water (Darwin’s “conditions of life”) to all biophysically constrained biodiversity. Researchers find potential path to repair multiple sclerosis-damaged nerves December 26, 2017 Multiple sclerosis is an autoimmune, neurodegenerative disease, characterized by distinct disabilities affecting walking, vision, and cognition, to name a few. MS patients differ markedly from each other regarding which disability affects them…

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Chromatin: The structure of DNA

Update on Inflammation and Degenerative Brain Disease Excerpt: While mapping connections of neurons has become the holy grail of current neuroscience, it is clear that communication of neurons with many other types cells is, also, vitally important to every aspect of brain function. My comment: Understanding dementia was placed into the context of understanding how virus-driven energy theft alters the de novo creation of olfactory receptor genes and causes the loss of function that is linked to all pathology via…

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Light energy-dependent active motifs

Active Motif claims that Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. See how the role of light is portrayed in LightSwitch™ Luciferase Assay System (with my emphasis) Excerpt 1) Combined with our large collection of miRNA Mimics and Inhibitors, you have everything needed to study miRNA-3´UTR interactions, validate miRNA targets, measure RNA stability, translation efficiency and the functional impact of miRNAs on a gene-by-gene basis. Excerpt 2) The…

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Stress-perturbed mitochondrial dysfunction

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress Excerpt: To visualize the stress-reactive profiles across genotypes, a heat map with hierarchical clustering of the mean relative difference “stress–resting” was generated, demonstrating that each mitochondrial defect induced a different amino acid response signature (Fig. 4F). In particular, the stress-reactive amino acid profile was most distinct in mice with the respiratory chain complex I ND6 defect. To determine which class of amino acids was most discriminatory between…

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