influenza virus

Energy-dependent coulombic, autophagic, polycombic healthy longevity

Mitophagy is the selective degradation of mitochondria by autophagy. See also this excerpt: Disorders in energy creation by mitochondria can cause cellular degeneration… Mitochondria do not create energy.  They link the creation of the sun’s anti-entropic virucidal energy to RNA-mediated cell type differentiation via biophysically constrained DNA repair. Energy-dependent autophagy links mitophagy to supercoiled DNA via the innate immune system and RNA-mediated repair of damaged DNA. Repair is nutrient-energy dependent. Separating mitophagy from autophagy is one way to prevent people…

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RNA-mediated terrorism

Obama Advisers Urge Action Against CRISPR Bioterror Threat For the past two decades, the government has focused its biodefense efforts on a list of known pathogens—such as anthrax, smallpox, and Ebola—declared by the Department of Health and Human Services and Department of Agriculture to have the “potential to pose a severe threat to public health and safety.” Government-funded research on these pathogens receives special scrutiny, and the National Institutes of Health limits researchers from conducting experiments that could make certain…

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Polycombic ecological adaptation as a science, not a theory (2)

Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of the β-globin cluster, we propose that the complex patterns of diversity observed in this genomic region arose from distinct functional constraints related with the intricate…

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Hypothesis free pseudoscience vs facts (1)

Old Earth Creationist (OEC) Peter Berean, thinks I should change the claims in my model of energy-dependent biophysically constrained RNA-mediate protein folding chemistry. He does not like the fact that my model explains all pathology in the context of virus-driven energy theft. If viral latency is not nutrient energy-dependent and controlled by the physiology of reproduction in species from bacteria to humans, I will change my claims. If someone explains what is wrong with my model, I will try to…

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Co-evolution and co-speciation replace neo-Darwinian nonsense

Tree-rings reveal secret clocks that could reset key dates across the ancient world It is perhaps easy to forget that we have co-evolved on this planet with micro-organisms, including bacteria, which may be either beneficial or harmful to us. Similarly, viruses cannot copy themselves without help from our cells. Without us, they simply wouldn’t exist. Watch as science journalists change evolution to co-evolution and biodiversity is portrayed as co-speciation. Theorists who missed the paradigm shift continue their desperate attempts to…

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Did “Nature” kill Steve Jobs? (2)

See also: Did “Nature” kill Steve Jobs? In my model of biophysically constrained energy-dependent protein folding chemistry and RNA-mediated cell type differentiation, the nutrient-dependent pheromone-controlled physiology of reproduction links the innate immune system to supercoiled DNA, which protects all organized genomes from virus-driven entropy. For comparison to my model, see: Evolution 2016 Videos (Indexed) Youtube videos Posters See also for comparison: Viruses Have Guided the Path of Human Evolution Excerpt: Whenever a viral epidemic tears through a community, there are…

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Amino acids and virus penetration

For an example of the ocean of information you must swim through to get to an important fact about virus-driven energy theft and all pathology, see: The bacteriophage ϕ29 tail possesses a pore-forming loop for cell membrane penetration (June 15, 2016) They cite “PrDOS: prediction of disordered protein regions from amino acid sequence” (2007). Excerpt: We have also developed a system to predict disordered regions from the amino acid sequence. Our system is composed of two predictors, that is, a…

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The Light and Darkness of “Evolution 2.0”

The light of evolution in the oft-cited work by Dobzhansky (1973) is the energy from sunlight. The sun’s biological energy links its anti-entropic virucidal epigenetic effects to RNA-mediated amino acid substitutions that differentiate all cell types in all individuals of all living genera. Excerpt from Dobzhansky (1973)  …the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla. ( p.…

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RNA-mediated theory killers (2)

RNA-mediated theory killers… This is a continuation that will become a series that links the million dollar paradox to the $100,000 prize offered for finding the origin of information at Evolution 2.0, which obviously will be a continuation of Schrodinger’s claims and Dobzhansky’s claims along with the claims of others I have repeatedly mentioned here. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity Reported as: Lifelong learning is made possible by recycling of histones Excerpt: “Histones and their…

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Understanding cell type differentiation

Understanding the Stem Cell Niche Description: Stem cells provide an attractive model to study human physiology and disease. However, technical challenges persist in the biological characterization and manipulation of stem cells in their native microenvironment. The Scientist brings together a panel of experts to discuss interactions between stem cells and external cues, and the role of the stem cell niche in development and disease. Topics to be covered include the molecular mechanisms of hematopoietic stem cell niche interactions and techniques…

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