Irvine

pH-dependent viral latency (7)

Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots  6/12/20 …we demonstrate that the RNA mutation-based APOBEC3A assay is applicable to clinical samples from cancer patients. Our study presents a strategy to follow the dysregulation of APOBEC3A in tumors, providing opportunities to investigate the role of APOBEC3A in tumor evolution… pH-dependent viral latency (7)