junk DNA

Exposing the 2nd Law to more ridicule (1)

Summary: Experiment demonstrates quantum mechanical effects from biological system Schrödinger (1944) linked the anti-entropic virucidal energy of sunlight from the physiology of pheromone-controlled reproduction in soil bacteria to all biodiversity. He then began to suspect that his colleagues, who displayed human idiocy, would kill him – if ever again he reasserted the facts. After 1944, Richard P. Feynman took a stand against the human idiocy, and lost. He was not killed, just ignored. Ignorance prevails. It always has. The virus-driven…

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Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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DNA repair via junk DNA (2)

See also: DNA repair via junk DNA (1) Recently Evolved Genes Identified From Drosophila yakuba and D. erecta Accessory Gland Expressed Sequence Tags (2006) Reported in Singer (2015) as: In 2006, Begun found some of the first evidence that genes could indeed pop into existence from noncoding DNA. Singer’s claim that genes automagically pop into existence is consistent with Masatoshi Nei’s conclusion in: Mutation-Driven Evolution …genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the…

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DNA repair via junk DNA (1)

Initiating DNA repair To communicate stress signals within cells, JNKs add phosphate groups to proteins, and the Rochester study found the amino acid residue on SIRT6 that is modified by JNK. They found an energy-dependent RNA-mediated amino acid substitution linked to the physiology of reproduction. It makes DNA repair and transgenerational epigentic inheritance of biologically-based cause and effect possible. The innate immune system, links RNA-mediated amino acid substitutions to supercoiled DNA and protection of organized genomes from virus-driven entropy. The…

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Center stage RNA-mediated events (since 1996)

‘Junk’ DNA now center stage Excerpt: The implications of these findings can be linked to medical conditions from chronic stress to neurodegenerative diseases. Anna Di Cosmo​’s group, Eugene Daev‘s group, and Bruce McEwen‘s group have linked RNA-mediated amino acid substitutions from atoms to ecosystems and all pathology in all living genera. In the early 90’s, Bruce McEwen told me how to validate my model of cell type differentiation by starting with gene activation. In, Effect of two pyrazine-containing chemosignals on…

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Effect and affect of a single base-pair change

Junk DNA: A Journey Through the Dark Matter of the Genome Hardcover – April 14, 2015 by Nessa Carey New Book on “Junk DNA” Surveys the Functions of Non-Coding DNA Review by Casey Luskin Excerpt: “We now know that in some cases just a single base-pair change in an apparently irrelevant region of the genome can have a definite effect” (p. 201) My comment: A single base-pair change “… appears to result in species-specific organism-level changes in skin, glands, and…

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Anti-entropic solar energy

“We have a group trying to model the mitochondrion” — Ulla Mattfolk Trash pickup problem Excerpt: “The PGAM5 protein would be regulated by an allosteric mechanism, in which its biological function would switch from activation of the PINK1/PARKIN pathway for removal of damaged mitochondria to the FUNDC1 pathway for removal of damaged mitochondria,” according to Hannink. “Peptides behave like drug molecules; any time you can identify a biological process that is regulated by a peptide, that peptide becomes a leading…

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De novo gene Creation sans evolution of genes via mutations

Where do genes come from? – Carl Zimmer The pseudoscientific nonsense touted in this video has been refuted by decades of experimental evidence. The experimental evidence links RNA-directed DNA methylation from nutrient-dependent amino acid substitutions to the de novo Creation of olfactory receptor genes and fixation of amino acid substitutions in the DNA of organized genomes. Fixation occurs via the nutrient-dependent pheromone-controlled physiology of reproduction in species from microbes to man. Evolution: Dynamics of De Novo Gene Emergence “…it was…

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