landscape

RNA-protein interactions reveal biophysical to ecological landscapes

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes RNA-protein interactions are tethered to DNA via ultra-high-throughput measurement of the RNA-protein interactions that link amino acid substitutions to cell type differentiation. Differences in affinity are often driven by sequence-specific changes in both association and dissociation rates that rapidly link bio-physical constrained RNA-mediated protein folding to models that provide “…generalizable insight into the biophysical basis and evolutionary consequences of sequence-function relationships.” This is the generalizable…

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Nothing new under the sun, except pseudoscientific nonsense

On the Importance of Being a Methodological Naturalist Posted on November 5, 2014 by David Sloan Wilson Excerpt: “…consider the flying spaghetti monster, a deity invented to poke fun at religion. It is ridiculous, but is there any way to prove that it doesn’t exist?” Conclusion: “If religious believers abandon methodological naturalism, then they are forced to deny not only the laws of physics and the facts biological evolution, but the histories of their own religions.” My comments: DS Wilson is…

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Soft atheism: a case for Creation

The Case for ‘Soft Atheism’ By GARY GUTTING   Excerpt: “…much as I admire Dawkins’s work in evolutionary biology and in enhancing the public understanding of science…” My comment: The case against evolution. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes Biophysical constraints that enable the intermolecular tethering of RNA to DNA also link the epigenetic landscape to the physical landscape of DNA via the conserved molecular mechanisms of RNA-mediated events in species from…

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Social experiences epigenetically effect gene networks

Networks of Genes Respond to Social Experiences October 13, 2013, from Searching for the Mind with Jon Lieff, M.D. Excerpt 1: “The gene networks of social experience are consistent through many animals.” My comment: Not just many animals; the gene networks of social experiences must be consistent in all animals that adaptively evolved. You cannot get from microbes to man with any consistent model of cause and effect until you realize that the molecular mechanisms that enable cause and effect…

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