Larry Young

Ecological adaptation: a new definition of heredity (4)

Experimentally Induced Metamorphosis in Axolotl (Ambystoma mexicanum) Under Constant Diet Restructures Microbiota Accompanied by Reduced Limb Regenerative Capacity (2018) Our results show that distinct bacterial communities inhabit individual organs of Axolotl and undergo substantial restructuring through metamorphosis. The restructuring during metamorphosis is biophysically constrained by feedback loops that link olfaction from food odors and pheromones Ecological adaptation: a new definition of heredity (4)

Energy-dependent physical and biophysical constraints (5)

Summary: Emmy Noethe’s theorems were developed in the early 1900’s. Richard Feynman inadvertently or purposefully alluded to them as examples of human idiocy. Discover Magazine resurrected the examples of human idiocy in a 2017 article. For comparison, Choi et al., (2017) support the claims that intercellular and interkingdom communication is energy-dependent and controlled by the Energy-dependent physical and biophysical constraints (5)

Antithetical conclusions (4)

Evidence for sex-specific genetic architectures across a spectrum of human complex traits …will need to disentangle whether sex genetic heterogeneity may arise as a consequence of interactions with genetic loci located on the sex chromosomes, differences in gene control due to differences in the sex-specific cellular environment, or more general differences in environmental exposures between Antithetical conclusions (4)

Ricki Lewis’ Time Machine (4)

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan Excerpt: The signal we observe is driven by rs429358, a non-synonymous Cys112Arg variant, which defines the ε4 allele and which has not previously been shown to be the causal variant influencing lifespan. See also: Gorilla Genome 2.0: Lessons for the Clinic? Excerpt: Ricki Lewis’ Time Machine (4)

Mystery machine vs model (3)

See Mystery machine vs model (2) Response of mammalian macrophages to challenge with the Chlorovirus ATCV-1. Excerpt: IMPORTANCE:   Virus infections that persist in and stimulate inflammatory factors from macrophages contribute to pathologies in humans. A previous study showed that DNA sequences homologous to Chlorovirus ATCV-1 were found in a significant fraction of oropharyngeal samples Mystery machine vs model (3)