learning and memory

The origin of information (5,4,3,2,1)

Summary: These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes. The claims about new biosynthetic pathways should be placed into the context of what is known about the energy-dependent origin of all pathways. Researchers may have solved origin-of-life conundrum …the conditions that produce nucleic acid precursors also create the starting materials needed to make natural amino acids and lipids. That suggests a single set of [light activated] reactions could have given…

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Energy-dependent physical and biophysical constraints (8)

Summary: The role of vitamin C in the treatment of pain: new insights links what is known about the “superfood” Spirulina (blue-green algae), which is grown in marine and freshwater environments, to the stability of all organized genomes via its biological activities, such as antioxidant, anti-diabetic, cholesterol-controlling and insulin resistance effects. The biological activities are energy-dependent and they link the anti-entropic virucidal energy of sunlight to all biodiversity via the pheromone-controlled physiology of reproduction and microRNAs in plants and animals.…

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Theistic evolutionists fight back and lose (3)

See also: Theistic evolutionists fight back and lose See also: Theistic evolutionists fight back and lose (2) For succinct representations of the claims made by people who are obviously biologically uninformed, see: 7/25/13 Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian…

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Energy-dependent alternative splicings 1996 – 2016 (2)

See also: Energy-dependent alternative splicings 1996 – 2016 Re: Rs3827760 is Val370Ala and EDARV370A No matter what it is called, Val370Ala may be the best example of how nutrient energy-dependent biophysically constrained pheromone-controlled viral latency protects all organisms from virus-driven energy theft and all pathology. For example, see: Genome recoding by tRNA modifications The succession of mRNA codons controls the synthesis of polypeptides through the complementarity between each of the 64 possible codon triplets and the tRNA anticodons that decode…

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2016 obfuscated facts about energy as information

Illumination of the fluorescent biomarker in green revealed that the adult mouse brain could be infected by Zika in a region called the subgranular zone of the hippocampus. Full of neural progenitor cells, this part of the brain is important in learning and memory. Credit: Laboratory of Pediatric Brain Disease at The Rockefeller University/Cell Stem Cell As reported by Bob Yirka in: Best of Last Year – The top Medical Xpress articles of 2016 a team of MIT biologists reported…

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More refutations of neo-Darwinian nonsense

New CRISPR–Cas systems from uncultivated microbes In bacteria, we discovered two previously unknown systems, CRISPR-CasX and CRISPR-CasY, which are among the most compact systems yet identified. Notably, all required functional components were identified by metagenomics, enabling validation of robust in vivo RNA-guided DNA interference activity in E. coli. Interrogation of environmental microbial communities combined with in vivo experiments allows access to an unprecedented diversity of genomes whose content will expand the repertoire of microbe-based biotechnologies. They discovered that energy-dependent RNA-mediated…

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Optogenetics: Let there be virucidal light!

NIH Awards $1.4M Grant to Support Optogenetics Research Excerpt: Synaptic plasticity, learning and memory are regulated by protein signaling in the brain. Many forms of learning disabilities and other mental diseases may be caused by abnormal protein signaling. To address these brain disorders and diseases, it is crucial to understand on a molecular level the underlying processes within the brain that are involved in learning and memory.” My comment: When someone like Anna Di Cosmo, John Hewitt or Bruce McEwen…

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Base pairs, olfaction and RNA thermometers

RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae (2014) Excerpt: The stem-loop can be stabilized by strengthening the base pairing between the fourU element and SD sequence through the substitution of G-C base pairs, and this results in an elevated melting temperature (10). Conclusion: RNA thermometers represent a simple yet elegant mechanism for controlling temperature-dependent gene expression and may be more widespread among pathogenic bacteria that interact with mammalian hosts than is currently known. See also:  MicroRNA Stability…

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Non-random pheromone-controlled cell type differentiation

Experience-Dependent Plasticity Drives Individual Differences in Pheromone-Sensing Neurons Aug 17, 2016   •Individual differences in cell types are not random •Sex differences in pheromone-sensing neurons are controlled by experience •Changes in specific cell types are governed via “use it and lose it” plasticity •Targeting plasticity to specific cell types changes animal behavior This was reported as: Long-term exposure to female scents changes courtship behavior in male mice The senior author co-authored Chromatin remodeling inactivates activity genes and regulates neural coding…

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The tipping point? 50,000 publications (5)

For review see my blog posts “The tipping point? 50,000 publications” with follow-ups: (2) (3) & (4). There are now more than 52,000 published works that link microRNAs to cell type differentiation in the context of healthy longevity or virus-driven energy theft, which has been linked from viral latency to all pathology. At the rate of ~1000 more publications per month that link energy-dependent changes in the microRNA/messenger RNA balance to healthy longevity or link virus-driven energy theft to all…

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