memory

The origin of information (5,4,3,2,1)

Summary: These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes. The claims about new biosynthetic pathways should be placed into the context of what is known about the energy-dependent origin of all pathways. Researchers may have solved origin-of-life conundrum …the conditions that produce nucleic acid precursors The origin of information (5,4,3,2,1)

MicroRNAs and the Cassandra syndrome (revisited)

Conclusion: Serious scientists can explain every aspect of energy-dependent biophysically constrained viral latency in the context of details about these pathways and everything that links changes from electrons to ecosystems in all living genera. Why are the serious scientists still challenged by “…the tendency of academia to reject any academic-like work from outside academia?” What MicroRNAs and the Cassandra syndrome (revisited)

Epigenetic facts vs variable recombination theories

6/14/13 Nutrient-dependent/pheromone-controlled adaptive evolution: a model ….the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of Epigenetic facts vs variable recombination theories

RNA-mediated adult learning, memory, and neurogenesis

Here is a way to assess the power of the media-industrial complex to suppress accurate representations of biophysically constrained biologically-based cause and effect. Wait to see whether this experimental evidence is reported in the science news, or how it is reported. Enriched Environment Increases PCNA and PARP1 Levels in Octopus vulgaris Central Nervous System: First RNA-mediated adult learning, memory, and neurogenesis

Energy-dependent chirality (2)

See Energy-dependent chirality 2013 MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination See also E. Ben-Jacob Ben-Jacob et al., have linked everything currently known about natural information processing from natural selection for energy-dependent codon optimality to healthy longevity and from virus-driven energy theft to mutations that cause cancer. See for comparison: LH Tsai Tsai laboratory Our primary Energy-dependent chirality (2)

Chromatin: The structure of DNA (2)

A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation Excerpt (with my emphasis): Highlights •    A histone H4K20me1-specific live-cell probe, H4K20me1-mintbody, was developed. •    Dynamics and replication timing of Xi were visualized. •    Critical amino acids for the stability and/or folding of the mintbody were revealed. Reported as: Catching histones by the tail: A Chromatin: The structure of DNA (2)

Did “Nature” kill Steve Jobs? (2)

See also: Did “Nature” kill Steve Jobs? In my model of biophysically constrained energy-dependent protein folding chemistry and RNA-mediated cell type differentiation, the nutrient-dependent pheromone-controlled physiology of reproduction links the innate immune system to supercoiled DNA, which protects all organized genomes from virus-driven entropy. For comparison to my model, see: Evolution 2016 Videos (Indexed) Youtube Did “Nature” kill Steve Jobs? (2)

RNA methylation

This is a brief history of events that led me to found the domain RNA-mediated.com with some follow-up on the latest news about cell type differentiation In 2012, I attended this minisymposium 006.Transcribing Memories: New Mechanisms of Activity-Regulated Gene Expression and Their Roles in Experience-Dependent Plasticity. Description: Activity-regulated gene transcription is essential for orchestrating the RNA methylation

Cytogenetic approaches link biosystems to ecosystems

Cytogenetic approaches for determining ecological stress in aquatic and terrestrial biosystems (Original Russian Text E.V. Daev, A.V. Dukelskaya, L.V. Barabanova, 2014, published in Ecologicheskaya Genetika, 2014, Vol. 12, No. 2, pp. 3–12.) For comparison see this open access review: Assessing vertebrate biodiversity in a kelp forest ecosystem using environmental DNA The Russian group seemed to Cytogenetic approaches link biosystems to ecosystems

RNA methylation, RNA-directed DNA methylation, learning and memory

sink testing Lab medicine The illegal practice of providing false test results on clinical specimens–eg, vials of blood, urine specimens, that were deliberately discarded–ie, down the sink, without actually testing them Pylori Story #1: Acid Attack Pylori Story #2: Journey to the Center of the Stomach The “Modern Synthesis” is analogous to sink testing in RNA methylation, RNA-directed DNA methylation, learning and memory