metabolism

Pseudoscientists ignore what serious scientists prove

Earlier today (8/14/16) I challenged a friend who stated that “scientists claim 65 million years of natural selection led from the demise of the dinosaurs to the evolution of humans.” I ineffectively tried to explain the difference between the claims of scientists, which are based on experimental evidence, and the claims of pseudoscientists, which are based on pseudoscientific nonsense. Last week, this same friend asked where the energy comes from that is released when hydrogen atoms are split. How did…

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RNA-mediated theory killers (5)

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression Reported as: Researchers elucidate network of genes that control when puberty begins Excerpt: …have identified for the first time members of an elaborate superfamily of genes that regulate the timing of puberty in highly evolved nonhuman primates. My comment: Who do these researches and science journalists think they are fooling when they report the nutrient-dependent pheromone-controlled onset of puberty, which is obviously RNA-mediated, in the context of highly evolved organisms?…

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Theorists can’t understand biology

See also: Neuroplasticity Thanks to Teresa Binstock for calling my attention to this:   Thanks to Anna Di Cosmo for calling the attention of others to this: My comment: Attempts to explain the “binding problem” of integration in the context of ecoimmunology and disease ecology compared to emergence and evolution are examples of how much pseudoscientific nonsense has been accepted and touted in the context of the neo-Darwinian “Modern Synthesis.” For comparison, serious scientists have detailed a model of top-down…

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The virome, microbiome, replisome and supercoiled DNA

First Complete Pictures of Cells’ DNA-Copying Machinery Excerpt: This architecture could also potentially play an important role in developmental biology by providing a pathway for treating the two daughter strands differently. Many modifications to DNA, including how it is packaged with other proteins, control which of the many genes in the sequence are eventually expressed in cells. An asymmetric replisome may result in asymmetric treatment of the two daughter strands during cell division—an essential step for making different tissues within…

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Skip the politics; embrace the facts

It’s Not Brain Surgery, Ben Carson Excerpt: …“Heal Inspire Revive,” invokes an image of him pounding on the chest of a pulseless America. Whether or not he actually knows how to handle a crash cart of that size, many voters don’t seem to doubt that he can. And he doesn’t doubt it either. My comment: I do not expect anyone who understands what is currently known about how physics and chemistry are linked to the biophysically constrained conserved molecular mechanisms…

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RNA Mediated

Metaphysical science vs theory

I’ve wasted too much time attempting to explain biologically-based facts to the biologically uninformed discussants on Science X network. This is an attempt to salvage some of the time and to move forward.  See: New comments posted on Science X network: – A natural history of neurons: Diverse mutations reveal lineage of brain cells : 1 new comment – Study sheds light on powerful process that turns food into energy : 1 new comment – Study adds to evidence that…

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Anti-entropic containment of energy: symbiosis 1.0

Scientists explore the origins of energy in chemical reactions using experimental quantum chemistry Excerpt: One thing that all chemical reactions have in common—whether they are the reactions that take place inside a battery, the metabolic reactions inside a living organism, or the combustion reactions that cause an explosion—is that they all involve some kind of change in energy. My comment: Therein lies the problem with attempts by pseudosceintists to link nutrient energy from ecological variation to epigenetically-effected ecological adaptation, which…

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The “great filter” is an epigenetic trap

The great filter The silence of universe seems ominous. Was Earth lucky? Thanks to George Ellis​ for alerting others to this. Excerpt: Nick Lane in his magnificent new book The Vital Question thinks that a peculiar feature of all earthly life — that it traps energy in the form of protons pumped across membranes… Excerpt 2) Next, after a couple of billion years, creatures bigger than microbes emerged, once (Nick Lane argues) an energy-per-gene limit was breached by the invention…

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RNA-mediated gene duplication, fixation, and ecological adaptation

Chromosomal Arrangement of Phosphorelay Genes Couples Sporulation and DNA Replication Excerpt: The simplicity of this coordination mechanism suggests that it may be widely applicable in a variety of gene regulatory and stress-response settings. Reported as: Bacteria use DNA replication to time key decision Excerpt: “Successful sporulation requires two complete copies of the bacterial chromosome, so coordination between the sporulation decision and the completion of DNA replication is very important,” Narula said. “A good analogy might be a semester-long course in…

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“New” epigenetic mechanism for lifelong learning?

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity Reported as: Lifelong learning is made possible by recycling of histones, study says Also reported as: New epigenetic mechanism revealed in brain cells Excerpt: In humans, researchers used a technique called 14C/12C bomb pulse dating to measure turnover. The technique is based on the fact that high levels of radioactive carbon (14C) were released into the atmosphere during the 1950s and 1960s, when open-air nuclear bomb testing occurred following the…

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