microbes to man

RNA-mediated species diversification from microbes to primates

Mycobacteriophage-drived diversification of Mycobacterium abscessus Biology Direct (15 September 2014) OPEN ACCESS Excerpt (with my emphasis): “Widespread occurrence of phage sequences in almost all studied M. abscessus complex isolates suggests that the rate of prophage invasion is faster than the rate of mutation, implying rapid evolution of M. abscessus.” My comment: The faster rate of prophase invasion suggests ecological adaptations occur more rapidly than evolution. That may be why no experimental evidence of biologically-based cause and effect suggests that evolution…

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Genes and Race: Human History?

Roundup of Book Reviews of Nicholas Wade’s A Troublesome Inheritance My comment: Many reviewers of Wade’s book on genes and race appear to think he has accurately represented issues of differences in cell types that evolutionary theorists associate with mutations, natural selection, and the evolution of human biodiversity. This may be cause for concern among those who are interested in accurate representations of biologically-based cause and effect. In this century, it has become clear that ecological variation results in biodiversity, which…

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MiRNAs methylation and ecological adaptation sans mutations

MiRNAs methylation and ecological adaptation sans mutations  “Our 2003 Molecular and Cellular Biology paper …opened the mechanistic ‘black box’ of the developmental origins of adult disease susceptibility, and firmly placed the word, epigenetics, in the vernacular of this research field.”  — Randy Jirtle (2009) Our 1996 Hormones and Behavior paper included a section on molecular epigenetics with evidence that attested to the involvement of epigenetics in the context of olfactory/pheromonal input and the developmental origins of hormone-organized and hormone-activated adult sexual behavior.…

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Cell-type differentiation

How Do You Know When You’ve Found Them All? A Question That Applies To Beetles and Cancer Genes Alike by Carl Zimmer Conclusion: “Cancer biologists and beetle experts are not all that different when you think about it. They walk the same foggy road together, a long way from the end.” My comment: Only the cancer biologists and beetle experts who believe in mutation-driven evolution are walking a road together. It’s not a foggy road. It’s brain fog that makes them similar.…

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Evolution: innovations may have non-adaptive origins (sans mutations)

Q & A: Evolution Makes Do By Chris Palmer Evolutionary biologist Andreas Wagner argues that many evolutionary innovations may have non-adaptive origins. Excerpt: “If exaptations are pervasive, then natural selection—which few doubt is critical for the preservation and spreading of traits—may not be that important for the origin of innovations in life’s history.” See also: Rapid detection of positive selection in genes and genomes through variation clusters Excerpt: “They occur in well-defined domains of a protein’s tertiary structure and show…

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