microbes

Virus-driven downsizing of the human brain (5)

Virus-driven downsizing of the human brain (3) (8/9/16) Virus-driven downsizing of the human brain (4) (4/23/17) Who the heck is James V. Kohl? Thanks for asking. Posted by u/Sphinx_for_hire 3 months ago I’m in biochemistry/toxicology and was reading up on LUCA (aka Last Universal Common Ancestor). While Googling the work of Nick Lane, I stumbled upon the following page absolutely flaying Lane’s and others’ LUCA theories. This guy, James V. Kohl, has many websites in which he writes about human…

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Environmental selection is natural selection

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk was published on April 23, 2018 The ectodysplasin A receptor (EDAR) gene has a range of pleiotropic effects, including sweat gland density, incisor shoveling, and mammary gland ductal branching. The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to…

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Energy-dependent physical and biophysical constraints (10)

Summary: The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis…— Eugene Koonin My comment: Viruses are not life forms. They steal the quantized energy that links sunlight to viral latency in the context of everything known to all serious scientists about the fact that Feedback loops link odor and pheromone signaling with reproduction See for comparison: Olfaction Warps Visual…

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Pseudoscientists fail to refute theistic evolution

Darwinism for the Genomic Age: Connecting Mutation to Diversification …the chief cause of our natural unwillingness to admit that one species has given birth to other and distinct species, is that we are always slow in admitting any great change of which we do not see the intermediate steps. (Darwin, 1859) Darwin put energy-dependent “conditions of life” before what is now known about natural selection for codon optimality. That is the chief cause for ignoring anything that neo-Darwinists claim about…

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Politicized science: The demise of RNA-mediated.com?

A post-Presidential election change indicates that politicized science in the USA may be the cause of the steady decline in the number of pages read on this domain. The decline is paired with an increased bounce rate each time I post anything that pits the science of creation against the pseudoscientific nonsense of neo-Darwinian theories. If this domain were used in the context of a social science experiment, the statistics would show that ridiculous theories have left the USA relatively…

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RNA-mediated “repurposing” is autophagy

Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning “self-devouring”[1] and κύτος kýtos, meaning “hollow”[2]) is the natural, regulated, destructive mechanism of the cell that disassembles unnecessary or dysfunctional components.[3] RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled RNA-mediated repurposing in microbes and adaptations in primate brains Selective reporting of inferences: examples of pseudoscience Autophagy Pioneer Wins Nobel See my comments: ..autophagy, the process by which a cell recycles unnecessary components. “His discoveries opened the path to understanding the fundamental importance…

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Hypothesis free pseudoscience vs facts (3)

Nobel-Winning DNA Research Challenges Evolutionary Theory In 2015, three scientists won the Nobel Prize in Chemistry for decades of research into DNA—research that reinforces the idea that evolution is mythology and makes the modern evolutionary theory of abiogenesis seem more and more indefensible. It turns out that DNA is inherently unstable, and the preservation of genetic information requires a complex symbiotic relationship between the cell and DNA that is so interdependent that neither could have arisen independently of the other.…

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Hydrogen-atom transfer in DNA base pairs (5)

Can Anybody Actually Win The Evolution 2.0 Prize? January 18, 2016 at 9:44 pm In an invited review of nutritional epigenetics, I linked atoms to ecosystems without the pseudoscientific nonsense touted by neo-Darwinists. Kohl, James V. (2014): Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. The invited submission was returned without review. When I provide all the details for the origin of the DNA code, what prevents the submission from being rejected without comment? January 18, 2016 at 11:13 pm …

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Nutrient-dependent trophic analogs

Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps Excerpt: Our results identify the molecular mechanism of epigenetic inheritance as the main target for therapeutic treatments against the emergence of adaptive resistance. Finally, our theoretical framework unifies known and newly identified determinants… Conclusion: Our model provides an explanation for the emergence of adaptive resistance based on the cost and benefit of the biological characteristics of an efflux pump system. It does not only predict the…

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More than a bag of chemicals?

From Fertilization to Adult Sexual Behavior (1996) Excerpt: “Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans…” My comment: How far can this model of RNA-mediated cell type differentiation go? What links the model to ADHD? Could it be a single amino acid substitution (see below)? If so, can the response to ADHD pharmacotherapy be predicted by what is…

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