MicroRNAome

George Church refutes theistic evolution

Wednesday Afternoon Lecture Series (WALS) – The future of genetic codes and BRAIN codes The NIH Director’s Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. The future of genetic codes and BRAIN codes (video) My comment on the video: Biophysically constrained genetic codes are brain codes. They George Church refutes theistic evolution

Co-evolution and co-speciation replace neo-Darwinian nonsense

Tree-rings reveal secret clocks that could reset key dates across the ancient world It is perhaps easy to forget that we have co-evolved on this planet with micro-organisms, including bacteria, which may be either beneficial or harmful to us. Similarly, viruses cannot copy themselves without help from our cells. Without us, they simply wouldn’t exist. Co-evolution and co-speciation replace neo-Darwinian nonsense

Energy-dependent RNA methylation (6)

After I published Nutrient-dependent/pheromone-controlled adaptive evolution: a model, Lynnette Ferguson and Justin O’Sullivan invited me to submit this review of nutritional epigenetics for inclusion in a special issue of the journal “Nutrients.” Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (April 10, 2014) Abstract: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic Energy-dependent RNA methylation (6)

Energy-dependent biodiversity (3)

Higher Abundance of Bacteria than of Viruses in Deep Mediterranean Sediments Conclusion: Results obtained in this study suggest that the number of viruses in deep-sea sediments might be dependent upon complex interactions with both abiotic factors (such as pressure, physical disturbance, and redox conditions) and biotic factors, including bacterial metabolic state and virus supply from Energy-dependent biodiversity (3)

RNA-mediated physics, chemistry, and molecular epigenetics (2)

9/16/15 This is an excellent introduction to speculation about how quantum mechanics might be linked from physics and chemistry to the conserved molecular mechanisms of epigenetically-effected biologically-based RNA-mediated cause and effect, which all serious scientists already know must link angstroms to ecosystems via the innate immune system, the physiology of reproduction, and supercoiled DNA. The RNA-mediated physics, chemistry, and molecular epigenetics (2)

Molecular Microbial Ecology

Second Genome Solutions Excerpt: Todd DeSantis is Second Genome Co-founder and Senior Director of Bioinformatics. Todd has 17 years of experience designing and implementing bioinformatics solutions for analyzing microbial community dynamics. At Lawrence Berkeley National Laboratory he led the development of novel microbiome assays and analysis pipelines as a Molecular Microbial Ecology Software Developer. He Molecular Microbial Ecology

Virus-perturbed alternative splicings

Computing in mammalian cells with nucleic acid strand exchange Abstract excerpt: …we established that functional siRNA could be activated through strand exchange, and used native mRNA as programmable scaffolds for co-localizing gates and visualizing their operation with subcellular resolution. Reported as: Scientists Demonstrate Basics of Nucleic Acid Computing Inside Cells Excerpt: Cells, of course, already Virus-perturbed alternative splicings

Center stage RNA-mediated events (since 1996)

‘Junk’ DNA now center stage Excerpt: The implications of these findings can be linked to medical conditions from chronic stress to neurodegenerative diseases. Anna Di Cosmo​’s group, Eugene Daev‘s group, and Bruce McEwen‘s group have linked RNA-mediated amino acid substitutions from atoms to ecosystems and all pathology in all living genera. In the early 90’s, Center stage RNA-mediated events (since 1996)