microRNAs

MicroRNAs GnRH and the failure of sex research

Summary: “The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression” accurately represents what is known about food energy-dependent RNA-mediated cell type differentiation in species from soil microbes to humans. MicroRNAs are not new players in the hypothalamic control of fertility and the effects of food odors and pheromones on microRNAs link energy-dependent changes in hormones to behavior. That fact was detailed two decades ago in our Hormones and Behavior review. Now see: [MicroRNAs: new players…

Read More

God’s shrinking role in salvation

God’s shrinking role in salvation can temporarily be placed into the context of what serious scientists are reporting for comparison to the claims of pseudoscientists. See: Quantum Simulation (free download) It presents several examples of experiments using both density and momentum imaging and quantum gas microscopy to study the motion of atoms in optical lattices. The energy-dependent motion of atoms must be linked to ecosystems by the physiology of pheromone-controlled reproduction in all living genera. That fact requires extended consideration…

Read More

From E. coli to monkeys and mankind: Theories vs models (4)

From E. coli to monkeys and mankind: Theories vs models (3)  More Complexity with Tau Tagging and un tagging occurs at Ser214, Thr231 and Ser262 at least in order to attach to microtubules in good neurons along the axon highways. Interactions of these affect the PSD as well such as Ser212/Thr214, Ser202/Thr205, and Thr231 by altering the tau interaction with the PSD. Tau is called a “microtubule associated protein”, one of many stabilizing and regulating the vast amount of shapes…

Read More

From E. coli to monkeys and mankind: Theories vs models

Hard Science: The Measure of All Things Natural w/Dr. J Michael Bailey (video) Published on 24 May 2017 First in a series of interviews DocAmitay had with Dr. J. Michael Bailey, controversial researcher who dares to ask questions that most do not dare to ask and that many do not want answered. The next few videos present a candid look at the man behind “the monster” created by Trans advocates, the media and those who oppose critical thinking and scientific…

Read More

Food energy-dependent epigenetic adaptation

Mechanism of transmembrane signaling by sensor histidine kinases, was reported as Scientists investigate how the sense of smell works in bacteria …the signaling and inactive states differ only very slightly at the nitrate-binding site – by 0.5-1 angstroms, which is approximately one fifth of the size of the ion itself (1 angstrom is 10-10 meters). However, when this ion binds to the sensor, it causes huge changes in the protein: The helices of different monomers begin to move in different…

Read More

Energy-dependent epigenetic translation to mRNA stability (2)

See first: Energy-dependent epigenetic translation to mRNA stability Universe’s ultraviolet background could provide clues about missing galaxies Simulations show that there should be more small galaxies in the Universe, but UV radiation essentially stopped them from developing by depriving them of the gas they need to form stars. UV light constrains the creation of galaxies and also biophysically constrains the creation of the mutations in cancer cells. When will Stephen Hawking and other biologically uninformed theorists admit that their ridiculous…

Read More

The death of CRISPR; long live endogenous RNAi

The future of human genome editing Published online 26 April 2017 …there are currently few genetic arguments for the necessity of correcting the genetic material of future generations given preimplantation diagnosis of monogenic conditions. The death of the CRISPR Cas9 may seem to have come quickly, but see also: Kalevi Kull: Censorship & Royal Society Evo Event Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of…

Read More

Feng Zhang refutes theistic evolution

Nucleic acid detection with CRISPR-Cas13a/C2c2 My summary: Their ability to detect single base differences links differences in the energy of photons to the light-induced de novo creation of RNA and to RNA-mediated amino acid substitutions that differentiate all cell types in all individuals of all living genera. Any claims about mutations and evolution have already been replaced by what serious scientists have learned about natural selection for energy-dependent codon optimality and the pheromone-controlled physiology of reproduction, which biophysically constrains all…

Read More

Cytosis: Biology content (2)

Cytosis is a [energy-dependent] transport mechanism for the movement of large quantities of molecules into and out of cells. There are three main types of cytosis: endocytosis (into the cell), exocytosis (out of the cell), and transcytosis (through the cell, in and out). See also: Cytosis: A Cell Biology Board Game 3/27/17 See also: Cytosis: Biology Content 4/4/17 Cytosis: A Cell Biology Board Game  4/12/17 A board game taking place inside a human cell! Players compete to build enzymes, hormones…

Read More

Functionally interdependent editing and methylation

Editing and methylation at a single site by functionally interdependent activities …cytosine 32 in the anticodon loop of Trypanosoma brucei tRNAThr is methylated to 3-methylcytosine (m3C) as a pre-requisite for C-to-U deamination. Formation of m3C in vitro requires the presence of both the T. brucei m3C methyltransferase TRM140 and the deaminase ADAT2/3. Once formed, m3C is deaminated to 3-methyluridine (m3U) by the same set of enzymes. ADAT2/3 is a highly mutagenic enzyme4, but we also show that when co-expressed with…

Read More