molecular biology

The origin of information (5,4,3,2,1)

Summary: These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes. The claims about new biosynthetic pathways should be placed into the context of what is known about the energy-dependent origin of all pathways. Researchers may have solved origin-of-life conundrum …the conditions that produce nucleic acid precursors also create the starting materials needed to make natural amino acids and lipids. That suggests a single set of [light activated] reactions could have given…

Read More
An evolutionary theory killer

Subatomic: From thermophiles to humans (2)

Summary: As more information about natural selection for energy-dependent codon optimality made it clear that food energy was essential for species survival, the theorists continued to refuse to use experimental evidence to support their claims about how mutations and natural selection could lead to the evolution of a new species. Now, the theorists are left with foolish claims, like this “…the universe simply is, without ultimate cause or explanation.” Why Is There Something, Rather Than Nothing? by Sean M. Carroll…

Read More

A mental health problem at the highest level (3)

Summary: It has been 75 years since Erwin Schrödinger exposed the pseudoscientific nonsense of mutation-driven evolution in the lecture series that was published as What is Life? (1944) The mental health of so-called science journalists must be addressed. Many of them seem to be pathological liars or, at best biologically uninformed science idiots who cannot link physics and chemistry from molecular epigenetics to all energy-dependent biodiversity on Earth. The Biggest Myth In Quantum Physics by Ethan Siegel Conclusion: Take ourselves…

Read More
For God and Country

Kinetically Stable Thermodynamically Activated Cell Metabolism (4)

Experience-dependent pauses link the de novo creation of enzymes to the de novo creation of G protein-coupled receptors that link olfaction and the visual integration of other sensory input. That fact has been placed into the context of the “hard-problem” of consciousness. See: What makes mosquitoes attracted to Platanthera orchids? Delivering pulses of specific chemicals (EAGs) to the mosquitoes also provided a better understanding of the way orchids attract and use the mosquitoes to get pollinated. Interspecific differences among orchid…

Read More
For God and Country

Kinetically Stable Thermodynamically Activated Cell Metabolism (1)

Excerpt: …via his failure to start from the creation of the sun, Philip Ball makes all aspects of food energy-dependent RNA-mediated error-free DNA repair disappear in his attempt to explain biodiversity, which starts with water. How to Cure Aging – During Your Lifetime? (video) This is a fascinating plea for funding. They seem to know that microRNAs regulate the energy-dependent microRNA/messenger RNA balance in species from plants to humans, but they don’t seem to know that the virus-driven theft of quantized…

Read More

From base editing to RNA editing (4)

Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” = 95 blog posts starting with In theory, or supported by experimental evidence? October 22, 2014 See for comparison PubMed: “base editing” (33 citations) and…

Read More

From base editing to RNA editing

Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine “Nature conveniently provides us with cytosine deaminase enzymes that operate on DNA,” Liu tells The Scientist. The creation of quantized energy in sunlight links energy as information from electrons to ecosystems via the physiology of reproduction in all living genera. The claim that “Nature” provides us with cytosine deaminase enzymes makes it seem that the enzymes emerged and automagically evolved to become purposeful and meaningful in the context of ridiculous theories…

Read More

Science vs Secularism: Molecular Mechanisms or Math?

Summary: An example from ancient knowledge of trigonometry links pattern recognition as the basis for the science of creationism, and pattern recognition also is the basis for molecular biology. What form of virus-driven pathology would you most like to see eliminated from future consideration by serious scientists who know how energy-dependent RNA-mediated cell type differentiation occurs? In any case, a PubMed search for microRNA and your disease of choice will be enlightening. See for example: microRNA + Alzheimer’s or microRNA…

Read More

UV light and non-coding RNA

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene …these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. Intriguingly, the switch between ASCC3 isoforms occurs on more than one level, in that the long mRNA isoform encodes a protein, functioning in the context of the ASCC complex and required for maintaining transcriptional suppression in the late stages of…

Read More

The death of human ethology via ecology

Nutrient-dependent/pheromone-controlled adaptive evolution: a model Open access publication on June 14, 2013 Mutation-driven evolution also published on June 14, 2013 Variable habitat conditions drive species covariation in the human microbiota http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005435 Open access publication on April 27, 2017 Conclusion: …we found that genetically related species respond to fluctuating habitat conditions in the same way, implying that they occupy similar ecological niches. Thus, current taxonomic groupings of bacteria are largely sufficient for explaining cross-sectional correlations in relative species abundances over the…

Read More