molecular

Ecological law, cooperation, and DNA repair

Ecological laws: what would they be and why would they matter? Abstract excerpt: … I argue, the existence of ecological laws would make ecological explanations irreducible to even the most complete possible physical explanations of the same phenomena. Ecological laws would make ecology genuinely autonomous from physics. My comment: This is a fool’s argument.  Serious Ecological law, cooperation, and DNA repair

Unified nutritional and molecular mechanisms

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits Article image: Excerpt: “…unifying nutritional and molecular mechanisms remain elusive.” Reported as Molecular mechanism behind health benefits of dietary restriction identified Excerpt 1) “Dietary restriction is a type of intervention that can include reduced overall food intake, decreased consumption of particular macronutrients such as protein, Unified nutritional and molecular mechanisms

It’s cell type differention, not cell fate determination (2)

See: It’s cell type differention, not cell fate determination High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions Excerpt: “…deviation from the derived models is a characteristic hallmark of methylation changes associated with cancer states suggesting that this phenomenon is mechanistically distinct from differentiation related methylation changes.” My It’s cell type differention, not cell fate determination (2)

New technique used in report of atomic-level ecological adaptations

Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons Directed evolution of a far-red fluorescent rhodopsin reported as: New technique uses a genetic tool and light to view and map neuronal circuits Excerpt 1): “This [directed evolution] experiment demonstrates how rapidly these remarkable bacterial proteins can evolve in response to new demands. New technique used in report of atomic-level ecological adaptations

Nutrient-dependent pheromone-controlled exercise-induced physiques

How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling Excerpt: “…cellular and molecular phenotype for exercise capacity is always acquired from regular exercise or muscle contraction; it is absurd to use drug and gene modification…” My comment: What is known about RNA-mediated events shows that the slightest Nutrient-dependent pheromone-controlled exercise-induced physiques

A molecular visualizer of worthwhile molecular biology

Ruben Gonzalez Jr.: Molecular Visualizer Associate Professor and Director of Graduate Studies, Department of Chemistry, Columbia University. Age 42 By Jef Akst | September 1, 2014 Excerpt: “Much of his group’s current work involves extending discoveries about translation in E. coli to the process in eukaryotes, with an eye toward human health and disease.” My A molecular visualizer of worthwhile molecular biology

RNA-mediated ecological adaptation is not evolution

Prehistoric Critters Change View of Mammal Evolution Three extinct squirrel-like species were identified from Jurassic-era fossils in China. By Molly Sharlach | September 12, 2014 Excerpt 1): “The fossils suggest that the slender animals spent time in trees, and had hands and feet adapted for grabbing branches. Their resemblance to present-day squirrels is a result RNA-mediated ecological adaptation is not evolution