Defeating disease and Communism (3)

More than 117,000 published works that mention ‘microRNA‘ can be linked from: Playing games with quantum interference 3/10/21 via MicroRNAs organize intrinsic variation into stem cell states 3/5/20 and MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 to the game for ages 14+ Genotype. Everything known to intelligent serious scientists has been linked to Defeating disease and Communism (3)

Geobiology vs Geovirology (1)

*Danger: Viruses may trump mankind* 8/9/14 “Many serious infectious diseases are our own doing. It is up to us to reinvigorate the fields of Virology, Bacteriology and Parasitology so that we will be prepared for the infectious challenges of the future and the clear and present dangers of today. Today’s clear and present danger of Geobiology vs Geovirology (1)

Autophagy is the antiphage defense strategy (2)

2/15/17 Energy as information and constrained endogenous RNA interference (video) The 6.46 minute-long technical presentation (above) from the Precision Medicine Virtual Conference is difficult to understand.Thus, 10 months later, Nik Willmore asked: 12/24/17 What are your insights into CRISPR and mTOR, for a young audience? I’m not mocking you…yet, Humpty Dumpty. What is the basis of your Autophagy is the antiphage defense strategy (2)

UV light and non-coding RNA

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene …these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. Intriguingly, the switch between ASCC3 isoforms occurs on more than one level, in that the UV light and non-coding RNA

Fighting for virus-driven pathology

See my series of 5 posts on the tipping point, which was reached when more than 50,000 indexed publications mentioned microRNAs The tipping point? 50, 000 publications May 16, 2016 See also: MicroRNA analysis in mouse neuro-2a cells after pseudorabies virus infection A total of eight viral miRNA were identified, and ten host miRNAs showed Fighting for virus-driven pathology

Re-inventing mutation-driven evolution (2)

See: Re-inventing mutation-driven evolution See also: Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp … we suspected that splicing efficiency, as defined by the fraction of pre-mRNA converted into mature mRNA, must have contributed to temperature-dependent Cirbp mRNA accumulation Splicing efficiency is energy-dependent in the context of temperature-dependent oscillations that link the Re-inventing mutation-driven evolution (2)