Pharmacogenomics: A road ahead for precision medicine in psychiatry 10/6/21 In this 2017 Precision Medicine Virtual Conference presentation, I linked the National Microbiome Initiative from microbial quorum sensing to the physiology of pheromone-regulated genetic processes of reproduction and endogenous RNA interference (#RNAi) via chromosomal rearrangements in flies from the works of Thomas Hunt Morgan (1910) … microRNA-mediated cures (7)
See first: Coherently organized healthy longevity (4) UV light, H2O, and epigenetic effects affect behavior and sympatric speciation Submitted by James V. Kohl on 9/25/20 for presentation during the Epigenetics – From Bench to Clinic session: RNA modifications and epitranscriptomics Moderator Tony Kouzarides Title: UV light, H2O, and epigenetic effects affect behavior and sympatric speciation … UV light, H2O, and epigenetic effects… (1)
Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent … Olfaction and microRNA signaling constrain longevity (1)
Autophagic cell death restricts chromosomal instability during replicative crisis 1/22/19 Our data suggest that autophagy is an integral component of the tumour suppressive crisis mechanism and that loss of autophagy function is required for the initiation of cancer. Reported as: In surprising reversal, scientists find a cellular process that stops cancer before it starts We … Epic failure of the FDA: Gottlieb resigns (1)
Summary: If the pathway is ancestral, how and when did it evolve to protect species from microbes to humans from the virus-driven degradation of their messenger RNA? Peer-Reviewed Science: A “Mathematical Proof of Darwinian Evolution” Is Falsified The theorem addresses only the effects of natural selection. Fisher did not directly address any other effect (mutation, … Quantized energy-dependent viral trophism (3)
Conclusion: There is no such thing as a blind dance of atoms. Quantized energy-dependent changes link angstroms to ecosystems in all living genera via the physiology of reproduction. Serious scientists do not link “high-level cause and purposes” to anything that does not link what organisms eat from food energy to the physiology of reproduction. Only … God’s shrinking role in salvation (2)
Premise: Sunlight is the energy as information that is required to link endogenous RNA interference to healthy longevity Counter claim: The Quantum Thermodynamics Revolution: Information theory Understanding entropy as a subjective measure allows the universe as a whole to evolve without ever losing information. Precision Medicine virtual conference, Feburary 22-23, 2017 Title: Energy as information … Energy as information and constrained endogenous RNA interference (4)
John Lieff has been trying to update his ridiculous misrepresentations of biologically-based cause and effect to match the accurate representations we made in a section on molecular epigenetics in our 1996 Hormones and Behavior review. From Fertilization to Adult Sexual Behavior Nothing can stop him, but this will provide the next source for material that … Light-activated feedback loops vs self-organization of ecosystems
No Evidence For Human Pheromones Excerpt from the comment by Stephan Biles: I also wonder about pheromones with human-animal interactions. The biophysical constraints are linked across species via the need to ecologically adapt to virus-driven energy theft. See: MicroRNAs in the Host Response to Viral Infections of Veterinary Importance Nutrient stress and social stress effect … Magnussen’s “Faith fools” keep the faith
The media-industrial complex attack CNN chief: Politicians should oppose Trump’s attack on media …Trump’s labeling of the media as the enemy of the state was unfortunate and dangerous. It was an accurate label that has been supported by Bill Gates and the Allen Institute in the context of the forthcoming viral apocalypse. See for comparison … The essence of precision medicine
