natural selection

From quantum physics to quantum souls (2)

May 29, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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Summary: Natural selection for food energy-dependent codon optimality links the physiology of pheromone-controlled reproduction to all biodiversity on Earth via gene splicing and energy-dependent RNA-mediated fixation of amino acid substitutions. How humans and apes are different, and why it matters (2018) …the most distinctive feature of humanity is its ability to significantly alter ecosystems. That exemplifies human idiocy. The most distinctive features of humanity are biophysically constrained by what people eat and the physiology of pheromone-controlled reproduction. See: Nothing in Biology…

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Epigenetic inheritance of spatiotemporal regulation

May 22, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Excerpt: The perception of time thus varies between people and may depend at least in part on personality. These results open up a new avenue for studying and manipulating how we process social situations. This could eventually benefit people who struggle with social interactions, such as those with autism spectrum disorders. Link opens the pdf: Olfaction Warps Visual Time Perception Concluding paragraph: In physics, space-time is warped by the distribution of mass and energy in it (Hwaking 1988). Our findings,…

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Environmental selection is natural selection (5)

April 30, 2018
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
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Summary: Atheistic Chinese Communists realize that vaccinations cannot protect them. Their attempts to develop a universal vaccine have failed. Bill Gates promotes vaccinations, which led us to the brink of the next pandemic. Vaccines prevent ecological adaptations in some cell types. Does Bill Gates, a non-scientist, think that people from God-fearing non-communist countries can do better than the atheistic Communists? Bill Gates calls on U.S. to lead fight against a pandemic that could kill 33 million Gates and his wife,…

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The eternal significance of microRNAs (4)

April 20, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Light Energy, microRNA editing, Model Organisms, RNA Directed
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Conclusion: Conserved energy biophysically constrains viral latency. Metatranscriptomics High-throughput sequencing and analysis of microbial community cDNA are providing valuable insight into in situ microbial activity and metabolism in the oceans. When faced with the eternal significance of quantized energy-dependent natural selection for codon optimality, theorists must attack the basics of what is known to serious scientists about biophysically constrained life on Earth. See for example: Virus-mediated archaeal hecatomb in the deep seafloor By starting with “raw assemblies” instead of the…

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For God and Country

Abiogenesis vs microRNA biogenesis (2)

April 20, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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All serious scientists learned about Schrödinger’s claims in “What is Life?” (1944).  All serious scientists have since linked the creation of the sun’s anti-entropic virucidal energy to “negentropy” and healthy longevity. See also: Reappraising the human mitochondrial DNA recombination dogma …paving the way for the definitive rejection of the non-recombination dogma for human mtDNA.   Recombination is quantized energy-dependent and biophysically constrained by the physiology of reproduction. See the works of those who are scheduled to present during Schrödinger at…

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From photons to the proton motive force (2)

March 9, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, What's in the News
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If you know someone who has linked differences in the energy of photons from the proton motive force to the physiology of reproduction and all biophysically constrained biodiversity, ask if they will attend Schrödinger at 75-The Future of Biology For contrast, touting genetic evolution is not the future of biology. See: Abstract: K06.00013 : A Path Integral Method for Analytically Tractable Inference of Evolutionary Dynamics Understanding the forces that shape genetic evolution is a subject of fundamental importance in biology…

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The MicroRNAome Strikes Back: A Sokalian hoax (8)

January 30, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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Defeating Diseases with Energy (January 9, 2018) is a thinly disguised attempt to help corporate giants continue to promote ridiculous neo-Darwinian theories. It features the works of Douglas C. Wallace, who failed to link the virus-driven degradation of messenger RNA to all pathology since he published: Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes (1990). Similar analysis of a cervical carcinoma (HeLa), fibrosarcoma (HT1080), and an Epstein-Barr virus (EBV)-transformed lymphoblastoid line (EBV-L) revealed that…

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The MicroRNAome Strikes Back: A Sokalian hoax (6)

January 25, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, RNA Directed
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The nature of nurture: Effects of parental genotypes Science  January 26, 2018 …nontransmitted alleles can affect a child through their impacts on the parents and other relatives, a phenomenon we call “genetic nurture.” It doesn’t matter what they call it, since there is no defined boundary between genetics and epigenetics. Reported as: You Are Shaped by the Genes You Inherit. And Maybe by Those You Don’t by Carl Zimmer January 25, 2018 A calf may inherit those milk-boosting variants from its mother. But…

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Diet-driven RNA interference and cancer prevention

January 14, 2018
James Kohl
RNA Directed
One Comment

The food energy-dependent creation of one enzyme is the key to the effective treatment and/or prevention of colorectal cancer. The creation of enzymes prevents the creation of viral microRNAs. The food energy-dependent creation of one or more enzymes limits the ability of different viruses to steal more quantized energy. That is the basis for my claims about biophysically constrained viral latency. Moreover, all pathology is caused by the virus-driven degradation of messenger RNA. See: Engineered commensal microbes for diet-mediated colorectal-cancer…

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Enzyme-constrained interethnic biodiversity (6)

January 12, 2018
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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I think that I may be able to finish this series before the end of the month and use my tweets to expose more than 100,000  people to what is known about how the energy-dependent creation of microRNAs prevents all pathology. See for one example of more than 68,000 published works: MicroRNA-22 suppresses cell proliferation, migration and invasion in oral squamous cell carcinoma by targeting NLRP3 For an extensive review of biologically-based biophysically constrained viral latency, see: Enzyme-constrained interethnic biodiversity…

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