nutrient-dependent

Epistemic corruption (8)

What don’t you believe about these facts from 1910? I posted this video to Facebook one year ago, after a trip across the United States, which I chronicled in a series of other videos. Since then, “Cellulose” has linked fixation of amino acid substitutions to construction of the cell wall and microRNA-mediated protein folding chemistry Epistemic corruption (8)

CDC’s ignorance: from roots to shoots (3)

Plenty of Room at the Bottom

Longtime AIDS researcher Robert Redfield picked to lead CDC 3/21/18 In the early days of the AIDS crisis, Dr Redfield…[failed to learn about biophysically constrained] …active HIV replication in all stages of HIV infection. All viral replication is energy-dependent and microRNA-mediated. Without realizing it, the director of the CDC linked food energy-dependent pheromone-controlled fixation of CDC’s ignorance: from roots to shoots (3)

microRNA-mediated sex differences (1)

For recent support of our claims from 23 years ago, see: Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier function and actin organisation (Dec 2019) We used our well established model of fetal endothelial cells isolated from placenta (fpEC) and analysed sexual dimorphic miRNA expression and potentially affected biological microRNA-mediated sex differences (1)

Quantum initiation of cold chemistry vs Hypeology (3)

See: Quantum initiation of cold chemistry vs Hypeology (2) Facts about the quantized energy-dependent creation of reverse transcriptase, an enzyme that converts a sequence in an RNA molecule into a sequence in a DNA molecule, have been placed into the context of social organization. Social organization: The thermodynamic basis The objective of this work is Quantum initiation of cold chemistry vs Hypeology (3)

The eternal significance of microRNAs (7)

Sales of human pheromone-enhanced fragrance products have been virtually eliminated by the pseudoscientific nonsense touted by neo-Darwinian theorists and Big Bang cosmologists. I may revisit their ridiculous claims at ScentofEros.com and Pheromones.com, but prefer to continue moving forward via my other domains: RNA-mediated.com and Autophagy.pro. Summary: 2018 Update: Sympatric speciation has been linked to species The eternal significance of microRNAs (7)

The eternal significance of microRNAs (1)

Common Allele Linked to Sugar Consumption Leads to Lower Body Fat, Higher Blood Pressure One energy-dependent change in a base pair is linked from the FGF21 rs838133 variant to microRNA-mediated changes in morphology and behavior. The quantized energy as information link from microRNAs to morphology and behavior is common to my mouse-to-human model of sympatric speciation. The eternal significance of microRNAs (1)

Complexity: Routes and Patterns (4)

Amino acid coevolution reveals three-dimensional structure and functional domains of insect odorant receptors (2015) …the current models are both consistent with available and new experimental data and offer a number of predictions – notably, through revelation of highly constrained residues (Supplementary Data 9–10) – to guide and visualise structure-function analyses of these unusual sensory receptors. Complexity: Routes and Patterns (4)

Laws of Biology / Rules of Life

Summary: Slide number 6 clearly states the “Levels of Biological Organization” that the “NSF’s 10 Big Ideas” finally places into the context of what has been known to all serious scientists for more than a century. Simply put, Hugo de Vries definition of mutation (sudden energy jumps) should never have been accepted as anything besides Laws of Biology / Rules of Life

Conceptual critique: Innateness vs the death gene (1)

Summary: The term innate is used in psychological explanations. The so-called explanations ignore facts about the light energy-dependent activation of endogenous substrates. The anti-entropic virucidal energy of sunlight links the endogenous substrates to biophysically constrained viral latency and healthy longevity via the physiology of reproduction in all living genera. “Proximate mechanisms” and “evolution” are terms Conceptual critique: Innateness vs the death gene (1)

Cryo-EM: Linking spatial and conformational constraints

Plenty of Room at the Bottom

On Darwin Day (2018) Carl Zimmer suggested use of the twitter hashtag #Istudyevolution to report whatever aspect of biology people were studying. For example, Richard Lenski reported that he studied adaptation in E. coli. When I told others that ecological adaptation is nutrient-dependent and pheromone-controlled in species from microbes to humans, he blocked me from Cryo-EM: Linking spatial and conformational constraints