odor receptors

Biological evolution as a philosophy, not a science

There is no indication in the abstracts that any of the presenters are going to address the facts that link quantised energy to polycombic ecological adaptation and virus-driven energy theft from hecatombic evolution to all pathology in all living genera. Virus-mediated archaeal hecatomb in the deep seafloor (2016) provides details on the hecatombin evolution of all patholgoy From Fertilization to Adult Sexual Behavior (1996) provides details on the polycombic ecological adaptation of all healthy longevity. For these experts to address…

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Energy-dependent cellular communication

Communication shapes sensory response in multicellular networks Significance Cells routinely sense and respond to their environment, and they also communicate with each other. Exactly how communication impacts sensing remains poorly understood. We study a population of fibroblast cells that responds to a chemical stimulus (ATP) and communicates by molecule exchange. Combining experiments and mathematical modeling, we find that cells exhibit calcium oscillations in response to not only the ATP stimulus but also, increased cell–cell communication. Our results show that, when…

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The Light and Darkness of “Evolution 2.0”

The light of evolution in the oft-cited work by Dobzhansky (1973) is the energy from sunlight. The sun’s biological energy links its anti-entropic virucidal epigenetic effects to RNA-mediated amino acid substitutions that differentiate all cell types in all individuals of all living genera. Excerpt from Dobzhansky (1973)  …the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla. ( p.…

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One amino acid substitution, genes, and brain activity

After a sip of milkshake, genes and brain activity predict weight gain Excerpt: …one-third of the population possesses a second genetic variant associated with fewer dopamine receptors. In these individuals it is response in the dorsal striatum, a region critical for forming habits, that predicts weight gain. People with this genotype are also more prone to addiction and impulsive behavior… My comment: The link from nutritional epigenetics to the metabolic networks and genetic networks that control behavior is clear. Behavior…

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A lighting requirement for life

Some Principles of Causal Analysis in Genetics (1936) Extract: high frequency radiation and particles of high velocity are very important components of the environment, causing heritable changes by a process called mutation. Even if we could conduct our experiments behind 30 metres of lead the fact that mutation has a temperature coefficient is enough to show that it depends in part on energy fluctuations which are uncontrollable. Mutations must be controlled. See also: Life on Earth – Flow of Energy…

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DNA Methylation and organized genomes

This open access review that is linked from the title (below) will appear in the next issue of Int J Biol Sci 2015; 11(5):604-617. doi:10.7150/ijbs.11218 It is a excellent, albeit incomplete, review of how nutrient-dependent RNA-directed DNA methylation and RNA-mediated amino acid substitutions link the epigenetic landscape to the physical landscape of DNA via the biophysically constrained chemistry of cell type differentiation and the physiology of reproduction in all genera. The review is incomplete because they do not start with…

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An epigenetic trap (the sequel)

I will post this “sequel” before the “prequel” about light-induced amino acid substitutions because more attempts are being made to deny that the fact my colleagues and I detailed how epigenetic traps links the morphology and behavior of species from microbes to man. Support for the link from one epigenetic trap to cell type differentiation was included in the molecular epigenetics section of our 1996 review, which detailed how RNA-mediated chromatin remodeling occurs. From Fertilization to Adult Sexual Behavior: Excerpt:…

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No understanding of biodiversity

No single explanation for biodiversity in Madagascar Excerpt: “The study is part of a larger body of research aimed at identifying the climate, geology and other features of the environment that help bring new species of plants and animals into being in an area, and then sustain once they’re there.” My comment: Like many studies, this one posits that new species automagically arise and are somehow sustained in ecological niches. Excerpt: “What governs the distribution of, say, a particular group of…

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Quantum physics meets Evolutionary Psychology News

Capturing the motion of a single molecule in real time as it oscillates from one quantum state to another September 18, 2014 Excerpt: “It also moves researchers a step closer to viewing the molecular world in action — being able to see the making and breaking of bonds, which control biological processes such as enzymatic reactions and cellular dynamics.” My comment: The making and breaking of bonds controls all biological processes. Luca Turin tried to do move researchers a step closer…

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Social experiences epigenetically effect gene networks

Networks of Genes Respond to Social Experiences October 13, 2013, from Searching for the Mind with Jon Lieff, M.D. Excerpt 1: “The gene networks of social experience are consistent through many animals.” My comment: Not just many animals; the gene networks of social experiences must be consistent in all animals that adaptively evolved. You cannot get from microbes to man with any consistent model of cause and effect until you realize that the molecular mechanisms that enable cause and effect…

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