olfactory receptor gene

Energy and neural plasticity

Summary: Food energy is required because proteins do not create themselves and virus-driven energy theft causes the degradation of messenger RNA in all living genera. See for comparison: Neural plasticity wanes with age, but increasing the protein Arc—abundant earlier in life—in the visual cortex of mice can fend off this decline. The restoration of neural plasticity requires the food energy-dependent pheromone-controlled de novo creation of genes. For example, see: Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees Desperate…

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Hard Science vs the neo-Darwinian “magic box”

Summary: Identical nucleotide sequences link energy-dependent changes in binding sites to different amino acids in different proteins. The binding sites are conserved in the orthologous mammalian genes. The in vivo structure of biological membranes and evidence for lipid domains Scientists investigate how the sense of smell works in bacteria Biogenic non-crystalline U(IV) revealed as major component in uranium ore deposits As presciently predicted in the works of Richard Feynman and Bruce McEwen, bacteria feed on something that allows them to…

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The futility of The Battlefield FB group

Apparently, Paul Hartley blocked me from further discussion of his OP about dinosaurs and gladiators before I could ask if he thought “The Battlefield” is a “false flag” group. Does anyone else think that?   If so, do you think it can survive publication of experimental evidence that links responsive supramolecular systems to stepwise changes in the assembly of metal complexes via induction of a light-driven rotary motor scaffold akin to the bacterial flagellum of P. fluorescens? See: Dynamic control…

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Magic, Miracle, or Molecular Mechanism?

The Miracles of Smell and Taste: Evolutionists Cannot Account for the Origin of the Sense of Smell Excerpt: Professor of Biology John T. Caprio of Louisiana State University states that initially, the sense of smell developed in order to identify amino acid-like chemical substances soluble in water. The ability to determine molecules floating in the air is an adaptation of that original mechanism.96 (p. 106) How The Nose Knows: Research On Smell Boosted Excerpt: In an interesting side note, Caprio…

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Human pheromone deniers: What’s next?

Adapted from Human pheromones: What should these idiots do next? RNA-directed DNA methylation and RNA-mediated gene duplication and RNA-mediated amino acid substitutions link the nutrient-dependent physiology of pheromone-controlled reproduction to morphological and behavioral phenotypes in species from microbes to humans. Why would any serious scientist claim that there is a need to find human pheromones? Does any serious scientist not realize that the molecular mechanisms that link ecological variation to ecological adaptation must be the same in all living genera?…

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Nutrient-dependent microRNAs control cell types

Nutrient-dependent/pheromone-controlled adaptive evolution: a model. Excerpt: “…the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. The role of the microRNA/messenger RNA balance (Breen, Kemena, Vlasov, Notredame, & Kondrashov, 2012; Duvarci, Nader, & LeDoux, 2008; Griggs et al., 2013; Monahan & Lomvardas, 2012) in adaptive evolution will…

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UV-light mutations and gene loss (not gain)

The Neanderthals live on in us March 13, 2015 Excerpt: “He opted instead for a medical degree and then a PhD at the University of Uppsala, where he was supposed to be probing the DNA secrets of a virus.” My comment: If he had done what he was supposed to be doing, he might have learned how viral microRNAs and nutrient-dependent microRNAs contribute to cell type differentiation in all cells of all individuals of all species. If he had done…

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RNA-mediated repurposing in microbes and adaptations in primate brains

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion Excerpt: “…the C-terminal 47 amino-acids of ARHGAP11B (after lysine-220) constitute not only a unique sequence, resulting from a frameshifting deletion (fig. S10), but also are functionally distinct from their counterpart in ARHGAP11A.” My comment: Co-author Svante Paabo is the senior author of this 2003 publication: Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees The 2015 publication was reported as: A gene for brain size only found…

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Drunks and Monkeys: Pseudoscientific nonsense

Drunks and Monkeys Understanding our primate ancestors’ relationship with alcohol can inform its use by modern humans. By Robert Dudley | June 1, 2014 Excerpt: “…if the right kinds of bacteria are also present, fermentation will stabilize certain foodstuffs (think cheese, yogurt, sauerkraut, and kimchi, for example).” My comment:  Epigenetic changes induced by ethanol in astrocytes link histone acetylation, DNA methylation, and non-coding microRNAs in the developing and adult brain from frugivory to the nutrient-dependent de novo creation of olfactory receptor genes in bats. The…

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MiRNAs methylation and ecological adaptation sans mutations

MiRNAs methylation and ecological adaptation sans mutations  “Our 2003 Molecular and Cellular Biology paper …opened the mechanistic ‘black box’ of the developmental origins of adult disease susceptibility, and firmly placed the word, epigenetics, in the vernacular of this research field.”  — Randy Jirtle (2009) Our 1996 Hormones and Behavior paper included a section on molecular epigenetics with evidence that attested to the involvement of epigenetics in the context of olfactory/pheromonal input and the developmental origins of hormone-organized and hormone-activated adult sexual behavior.…

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