Parkinson’s Disease

Autophagy in health and disease (1)

Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors Each of these pathways have an intimate relationship with the programmed death pathways of autophagy and apoptosis and share a common link to the silent mating type information regulation 2 homolog 1 (Saccharomyces cerevisiae) (SIRT1) and the mechanistic target of rapamycin (mTOR). Circadian clock genes are necessary to modulate autophagy, limit cognitive loss, and prevent neuronal injury. Non-coding RNAs can control neuronal stem cell…

Read More

Energy-dependent physical and biophysical constraints (2)

Summary: The mind does not exist in nature. It is a manifestation of how ecological variation must be linked to the creation of food energy-dependent pheromone-controlled ecological adaptations. Energy-dependent physical and biophysical constraints (1) The energy-dependent de novo creation of all receptors is biophysically constrained. See: Channel opening and gating mechanism in AMPA-subtype glutamate receptors This was reported as: Scientists capture first image of major brain receptor in action Defects in glutamate receptors, or the processes they mediate, are implicated…

Read More

Life is energy-dependent task management (2)

See: Life is energy-dependent task management See also: New device detects bacteria and tests for antibiotic resistance When bacteria are caught, the device sends out three different signals to researchers. When bacteria is detected the cantilever’s mass changes, and it bends, explained Thomas Thundat, a professor in the Department of Chemical and Materials Engineering and the Canada Excellence Research Chair in Oil Sands Molecular Engineering. “So this gives us two signals: the mass change and the bending action.” By shining…

Read More

Nutrient-dependent life vs virus-driven pathology

Young Earth Creationists killing Christian credibility? Perry Marshall says: March 19, 2016 at 10:04 am James, you are one step away from being banned because of your disingenuous comments, your accusations, and your unnecessary combativeness. I am getting tired of it. People accuse you of being a troll for a reason. This is your final warning. My comment: Thanks for the warning, Perry Marshall. People who do not like me to disseminate accurate information about biologically-based cause and effect accuse…

Read More