pathology

Dobzhansky 1973 and precision medicine (4)

See: Dobzhansky 1973 and precision medicine (3) Evidence-based medicine has been hijacked: a report to David Sackett Fake news See for comparison: Sugar Gliders, Flying Squirrels, and How Evolutionists Explain Away Uncooperative Data …contradictory evidence drives evolutionists to embrace irrational just-so stories. Natural selection cannot “adapt” anything. Natural selection kills off the bad designs. It cannot influence the random mutations that must, somehow, come up with such amazing designs. This is the hard reality, but in order to rationalize the…

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Trump’s appeal to common sense (2)

See: Trump’s appeal to common sense Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation To our knowledge, this is the first study to use a genetic mouse model to simultaneously map Gpr182 localization patterns and elucidate novel physiological functions for the negative regulation of intestinal proliferative capacity, especially during regeneration and adenoma formation. Future studies to identify the ligand for this exciting and physiologically relevant orphan GPCR [G protein-coupled receptor] will shed light on its tractability as…

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Mutations: the “driving force” behind human brain complexity?

Evolutionary Psychology Crap in New Scientist There is a reason why domestic violence is so widespread, says David Buss, an evolutionary biologist at the University of Texas in Austin: it carries a selective advantage, tied with reproductive success. Larry Moran wrote: There’s something seriously wrong with evolutionary psychology. And there’s something seriously wrong with respectable science magazines who promote this crap. Are the science magazines that promote this crap respectable? I lost respect for anyone who still uses de Vries…

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Theorists sell hidden energy

Dan Rather on Journalism & Finding the Truth in the News Learn to ask the right questions & tell captivating stories. I have rarely been asked a question by any journalist. For comparison, many theorists and antagonists claim my truthful answers are wrong. The fact that journalists don’t ask the right questions and the fact that theorists assume truthful answers are wrong leaves many people with doubts about evolution. Many more people have become frightened by the fact that they…

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Anti-entropic energy and the “Music of Life”

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells … we report the existence of a TRIM28-controlled gene regulatory network based on ERVs that is active in hNPCs. Our findings open up for several exciting future studies on the role of ERVs as potential drivers of human brain evolution, their contribution to individual variation, and the implication in human brain disorders. All gene regulatory networks are energy-dependent. They must link the sun’s anti-entropic virucidal…

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Energy-dependent chirality

See also: Achiral glycine Summary: Virus-driven energy theft alters the interactions between physics and chemistry that maintain biophysically constrained biodiversity. That’s how viruses are linked from mutations to all pathology. Nutrient energy-dependent changes in the context of the pheromone-controlled physiology of reproduction biophysically constrain biodiversity via the fixation of amino acid substitutions in supercoiled DNA, which protects organized genomes from virus-driven pathology. Chirality (chemistry) Two enantiomers of a generic amino acid that is chiral The chirality of amino acids is energy-dependent…

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Vietnam Veterans and others with glioblastoma

The Agent Orange Widows Club After their husbands died of an aggressive brain cancer, the widows of Vietnam veterans have found one another as they fight the VA for benefits. See also: Vietnam Veterans with Glioblastoma Multiforme Stage 4 Brain Cancer This post was removed: Targeting NF-κB in glioblastoma: A therapeutic approach This is the level of complexity that the VA needs to understand and link to the treatment of this aggressive cancer, which is obviously caused by virus-driven energy theft.…

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Energy-dependent sensory maps (1996-2016)

Developmental broadening of inhibitory sensory maps My summary: They help to detail how olfactory input causes the energy-dependent de novo creation of sensory maps, which are representations of the external world. The experience-dependent representations link chemotaxis and phototaxis to biophysically constrained behavior. The representations are systematically organized in brain structures throughout development. Simply put, the maps are links from the epigenetic landscape to the physical landscape of supercoiled DNA in organized genomes. By investigating how ongoing neurogenesis in the mouse…

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2016 obfuscated facts about energy as information

Illumination of the fluorescent biomarker in green revealed that the adult mouse brain could be infected by Zika in a region called the subgranular zone of the hippocampus. Full of neural progenitor cells, this part of the brain is important in learning and memory. Credit: Laboratory of Pediatric Brain Disease at The Rockefeller University/Cell Stem Cell As reported by Bob Yirka in: Best of Last Year – The top Medical Xpress articles of 2016 a team of MIT biologists reported…

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More refutations of neo-Darwinian nonsense

New CRISPR–Cas systems from uncultivated microbes In bacteria, we discovered two previously unknown systems, CRISPR-CasX and CRISPR-CasY, which are among the most compact systems yet identified. Notably, all required functional components were identified by metagenomics, enabling validation of robust in vivo RNA-guided DNA interference activity in E. coli. Interrogation of environmental microbial communities combined with in vivo experiments allows access to an unprecedented diversity of genomes whose content will expand the repertoire of microbe-based biotechnologies. They discovered that energy-dependent RNA-mediated…

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