pathology

Autophagy is the antiphage defense strategy

The “Antiphage Defense Strategy” in Vibrio anguillarum is called autophagy by many serious scientists. It links nutrient energy-dependent pheromone-controlled quorum sensing to viral latency, healthy longevity, symbiosis, reproduction, and biodiversity from microbial species to humans. For an evolutionary approach to energy-dependent autophagy that fails to address any aspect of how virus-driven energy theft causes all pathology see: (12/7/16) Part I: Living together: The symbiosis of host-microbial interactions (12/7/16) See also: 12/7/16 ….McFall-Ngai tells the story of a symbiosis between the…

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Theories vs facts about polycombic adaptation

See: Demoncrats fight polycombic ecological adaptation Exosomes as miRNA Carriers: Formation–Function–Future Important aspects will be highlighted as a take-home message (THM) at the end of each paragraph. THM: Extracellular vesicles transport miRNA in a paracrine and endocrine manner. Questions regarding the cellular options of producing either microvesicles or exosomes and their difference in miRNA composition and number are still unknown. In my 2014 invited review, the four F’s, Formation–Function–Future and Copulation were included in details about how the nutrient energy-dependent…

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Politicized science: The demise of RNA-mediated.com?

A post-Presidential election change indicates that politicized science in the USA may be the cause of the steady decline in the number of pages read on this domain. The decline is paired with an increased bounce rate each time I post anything that pits the science of creation against the pseudoscientific nonsense of neo-Darwinian theories. If this domain were used in the context of a social science experiment, the statistics would show that ridiculous theories have left the USA relatively…

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Combating evolution: Battlefield medicine vs politicized science

A steady decline in the number of pages read on this domain is paired with an increased bounce rate each time I post anything that pits the science of creation against the pseudoscientific nonsense of neo-Darwinian theories. If this domain were used in the context of a social science experiment, the statistics would show how theories have left the USA relatively defenseless against the threat of gene-editing technology, which has has been advanced in countries where students are not taught…

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The futility of The Battlefield FB group

Apparently, Paul Hartley blocked me from further discussion of his OP about dinosaurs and gladiators before I could ask if he thought “The Battlefield” is a “false flag” group. Does anyone else think that?   If so, do you think it can survive publication of experimental evidence that links responsive supramolecular systems to stepwise changes in the assembly of metal complexes via induction of a light-driven rotary motor scaffold akin to the bacterial flagellum of P. fluorescens? See: Dynamic control…

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Metabolic Phenotyping Research

Global Consortium to Conduct Metabolic Phenotyping Research Consortium members in six countries will use chromatography, mass spectrometry, and other technologies to conduct metabolic phenotyping research that examines the dynamic interactions between genes, environments, microbiomes, diets, and lifestyles, and their collective impact on disease. My Predictions. 1. They will link energy as information to healthy longevity. 2. They will report their findings as if they discovered new molecular mechanisms. 3. The mechanisms will link the anti-entropic virucidal energy of ultraviolet light…

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Happy biophysically constrained Thanksgiving (in the USA)

Is there any other holiday in the world that celebrates biophysically constrained cell type differentiation in all living genera? The availability of amino acids and proteins in new genes is nutrient energy-dependent. The de novo creation of genes is biophysically constrained by the innate immune system and the physiology of reproduction. That fact was detailed for a general audience in Biblical Genesis. Today, all of us can be thankful that the pseudoscientific nonsense of neo-Darwinian theory was replaced earlier in…

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De novo gene creation: Ignoring the experimental evidence

Regularly Whiffing Essential Oils Can Retrain Lost Sense of Smell It’s not entirely clear how olfactory training works on a neurological level. Olfactory training links the experience-dependent de novo creation of G protein-coupled receptors to supercoiled DNA. Conserved molecular mechanisms link food odors and pheromones from the innate immune system to the physiology of reproduction. Simply put, autophagy protects all organized genomes from virus-driven entropy and all pathology via the de novo creation of odor receptor genes. See for proof:…

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Energy-dependent purifying selection / autophagy (5)

See: Energy-dependent purifying selection / autophagy (4) See also: Team develops method to better identify genes involved in diseases If we can pinpoint the genetic mutations that cause a particular disease, we can associate those mutations with specific proteins, and then design drugs to block or activate those proteins. We can also measure the activity of proteins identified in this manner to diagnose diseases more accurately, which is a major goal of precision medicine. In: Histone Acetylome-wide Association Study of…

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Energy-dependent purifying selection / autophagy

This is a multi-part series. See also: Energy-dependent purifying selection / autophagy (2-6) Pain from Cells that Are Not Neurons Introduction: Recent research on pain shows a very surprising result. A new type of neuroplasticity has been discovered… My comment: It’s discovery does not make it a new type of neuroplasticity. Discoveries like this attest only to the ignorance of theorists who have never considered the role that virus-driven energy theft plays in all pathology. Excerpt 1) Injuries produce ATP…

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