Comprehensive serological profiling of human populations using a synthetic human virome Excerpt from the editor’s summary: Despite differences in the rates of exposure to specific viruses, the antibody responses in most individuals targeted the same viral epitopes. My comment: Received: Fri, 05 Jun 2015 14:19:20 -0400 From an even broader perspective, this may be a … Creating and maintaining the human virome
Follow up to: Methylation maintains cell type differences Brain’s ‘gender’ may be quite flexible: Mechanism that plays key role in sexual differentiation of brain described Excerpt: “Prof. McCarthy is now doing additional research on the links between the immune system and brain sex differences.” See also: An immune hypothesis of sexual orientation Excerpt: “…this ICS-hypothesis … Methylation maintains cell type differences (2)
Characterisation of two Neurogenin genes from the brook lamprey Lampetra planeri and their expression in the lamprey nervous system by Ricardo Lara Ramirez et al. Abstract excerpt: “Here we report the isolation of two Neurogenin genes, LpNgnA and LpNgnB, from the lamprey Lampetra planeri. Phylogenetic analyses show both genes have orthologues in other lamprey species … 2 genes in 2 species (too expensive and too insignificant)
“We have a group trying to model the mitochondrion” — Ulla Mattfolk Trash pickup problem Excerpt: “The PGAM5 protein would be regulated by an allosteric mechanism, in which its biological function would switch from activation of the PINK1/PARKIN pathway for removal of damaged mitochondria to the FUNDC1 pathway for removal of damaged mitochondria,” according to … Anti-entropic solar energy
Thanks to Joost G. Wouters for the alert to this nonsense: 1) Michael White in Pacific Standard magazine flatly states that “Epigenetics Is Not Revolutionizing Biology.” 2) Adrian Bird points out in the journal Cell that many of the field’s assumptions and promises remain unproven and are perhaps excessive. 1) White’s article sketches the field’s … Epigenetics Skeptism
Participation on the FB group Thinking Allowed Original led to an invite by Ulla Mattfolk to participate on her secret group Quantum Biology, coherence and decoherence. On January 22 at 11:45pm, discussion led me to ask whether biophotonic energy differences could be recognized by the photons at the quantum level of their interactions/energies. I thought the answer might explain biodiversity via a … Physicists: Desperate Acts
Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits Article image: Excerpt: “…unifying nutritional and molecular mechanisms remain elusive.” Reported as Molecular mechanism behind health benefits of dietary restriction identified Excerpt 1) “Dietary restriction is a type of intervention that can include reduced overall food intake, decreased consumption of particular macronutrients such as protein, … Unified nutritional and molecular mechanisms
High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry Excerpt: “We use this technique to show modulation of a microRNA critical for T-cell function, miR-155. We adapt this assay for simultaneous detection of mRNA and proteins by ImageStream technology.” Reported as: Technology breakthrough reveals cellular transcription process My comment: Their … Single-cell level assay of protein biosynthesis and degradation
Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes Excerpt: “The CDP showed a significant overrepresentation of certain gene ontology (GO) groups (global tests Po0.001–0.009), using the programme FUNC23 (Methods). These groups included GPCRs, in particular olfactory receptors (ORs), and other membrane and cell-surface proteins, as well as proteins related to the immune … Dual genomes: exposing the evolution industry
Last year, Vosshall’s group eliminated ideas about the involvement of beneficial mutations in the nutrient-dependent cell type differentiation of mosquitoes. orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET. This year her group showed that nutrient-dependent amino acid substitutions clearly are involved in cell type differentiation. Evolution of mosquito preference … Epigenetic pharmacology and RNA-mediated transciptional landscapes
