physical landscape

Polycombic ecological adaptation as a science, not a theory

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Multi-omic data integration enables discovery of hidden biological regularities   Excerpt: Tracing the central dogma of biology (left column), we can link specific data types (middle column) to explain each of these biological processes. In this work, novel biological regularities that relate these processes are discovered through: (i) primary omics data (top box, right column) … Polycombic ecological adaptation as a science, not a theory

Attacking Young Earth Creationists

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‘Residual diversity estimates’ do not correct for sampling bias in palaeodiversity data Abstract excerpt: Evolutionary dynamics such as speciation are inherently a phylogenetic process, and only an explicitly phylogenetic approach will correctly model this process. Reported as: Flawed analysis casts doubt on years of evolutionary research The method assumes that variations in the number of … Attacking Young Earth Creationists

Light energy-induced base pair changes (2)

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See: Light energy-induced base pair changes (1) To help others move forward via the concept of energy-dependent biophysically constrained RNA-mediated protein folding and what is known about how virus-driven energy theft is linked to all pathology, see also: Subatomic Particles, Part 1: Leptons Subatomic Particles, Part 2: Baryons, the Substance of the Cosmos Subatomic Particles, … Light energy-induced base pair changes (2)

Light energy-induced base pair changes (1)

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Semisynthetic organisms and synthetic biology Unintended Consequences of Expanding the Genetic Alphabet Conclusion: …phototoxicity results presented herein using a human skin cancer cell line are intended to create awareness to the scientific community of the potential unintended consequences of expanding the genetic alphabet with unnatural nucleosides like those used in this work. Reported as:  Unintended consequences … Light energy-induced base pair changes (1)

Biophotonics, glycobiology, quantized biodiversity (2)

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From Fertilization to Adult Sexual Behavior (1996) In our section on Molecular epigenetics, we wrote: Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; … Biophotonics, glycobiology, quantized biodiversity (2)

Did “Nature” kill Steve Jobs? (2)

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See also: Did “Nature” kill Steve Jobs? In my model of biophysically constrained energy-dependent protein folding chemistry and RNA-mediated cell type differentiation, the nutrient-dependent pheromone-controlled physiology of reproduction links the innate immune system to supercoiled DNA, which protects all organized genomes from virus-driven entropy. For comparison to my model, see: Evolution 2016 Videos (Indexed) Youtube … Did “Nature” kill Steve Jobs? (2)

Energy-dependent creation and entropy

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Theorists tend to use the term de novo when they don’t know. If they don’t know how energy-dependent structures and functions are created, functional structures are created de novo. See for example:  Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection If theorists don’t know what causes mutations, … Energy-dependent creation and entropy

RNA-mediated physics, chemistry, and molecular epigenetics (2)

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9/16/15 This is an excellent introduction to speculation about how quantum mechanics might be linked from physics and chemistry to the conserved molecular mechanisms of epigenetically-effected biologically-based RNA-mediated cause and effect, which all serious scientists already know must link angstroms to ecosystems via the innate immune system, the physiology of reproduction, and supercoiled DNA. The … RNA-mediated physics, chemistry, and molecular epigenetics (2)

Neuroscience Virtual Event vs AAAS Symposium

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Neuroscience Virtual Event Abstract Submission Poster title: From hydrogen-atom transfer in DNA base pairs to ecosystems (March 16-17, 2016) Abstract: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on DNA base pairs in solution and RNA-mediated amino acid substitutions to chromosomal rearrangements via pheromone-controlled changes in the microRNA / messenger RNA balance. … Neuroscience Virtual Event vs AAAS Symposium