physics

From optoribogenetics to HelioRiboGenetics (4)

October 6, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, RNA interference
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The 2020 Nobel Laureates in Physiology or Medicine failed to link God’s Creation of energy-as-information in ultraviolet (UV) light and His Creation of water to biophysically constrained viral latency across kingdoms via oxidative phosphorylation and RNA interference. See for comparison: Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers 9/30/20 Conclusion The data indicate that PPMO have the ability to potently and specifically suppress SARS-CoV-2 growth and are promising candidates for further pre-clinical development. If the history of published…

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The tipping point (revisited): 102K (1)

May 15, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference, RNA-mediated gene silencing
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See first:  The tipping point (revisited): 101K (1) 4/22/20 and Vaccines do not control pandemics (1) 5/15/20 Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion 5/11/20 They linked virus-driven changes in light-activated energy-dependent differences in hydrogen-atom transfer in DNA base pairs in solution from microRNA flanking sequences to the degradation of messenger RNA and all obesity-linked diseases via changes in the potential of hydrogen (pH). See: Control of pH responsive peptide self-association…

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Quantum initiation of cold chemistry vs Hypeology (3)

June 21, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed
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See: Quantum initiation of cold chemistry vs Hypeology (2) Facts about the quantized energy-dependent creation of reverse transcriptase, an enzyme that converts a sequence in an RNA molecule into a sequence in a DNA molecule, have been placed into the context of social organization. Social organization: The thermodynamic basis The objective of this work is to establish the connection between energy engineering and social organization and to bring social organization under the big tent of physics. Reported as: How physics…

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The concept of a species (2)

June 12, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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The science of peaceful coexistence among members of the same species and human populations that are vilified starts with an understanding of the birds and the bees, which seems to be beyond the ability of neo-Darwinian theorists and Big Bang cosmologists to grasp. See for comparison: Birds from different species recognize each other and cooperate Article excerpt 1): Australian fairy-wrens not only recognize individual birds from other species, but also form long-term partnerships that help them forage and defend their…

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Complexity: Routes and Patterns (5)

May 31, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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Summary: Complexity does not emerge.Top-down causation is energy-dependent. Geoge FR Ellis, who co-authored The Large Scale Structure of Space-Time (1973) with physicist Stephen Hawking, just refuted every aspect of neo-Darwinian pseudoscientific nonsense and Big Bang cosmology by linking the creation of the sun’s anti-entropic virucidal energy to the complex metabolic regulatory networks of cellular function. Bacterial self-organization: co-enhancement of complexification and adaptability in a dynamic environment (2003) Learning from Bacteria about Natural Information Processing (2009) Focusing on the energy, matter,…

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Polymaths and paradigm shifts: from Asimov to Bear (2)

March 14, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Polymaths and paradigm shifts: from Asimov to Bear (1) See also: Search results for virus-driven energy theft Summary: The creation of enzymes, such as ATP synthase is energy-dependent. The energy biophysically constrains viral latency via the creation of microRNAs and RNA-mediated amino acid substitutions that differentiate the cell types of all living genera. Modifying Other’s Originality without Quote is an Act of Piracy A writer who does not cite the sources in h/h feature article is committing piracy. Piracy is…

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An evolutionary theory killer

Subatomic: From thermophiles to humans (3)

February 13, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Summary: RNA-mediated cell type differentiation in species from insects to primates can be linked from claims about the lower percentage of food energy-dependent DNA methylation in Diet and cell size both affect queen-worker differentiation through DNA methylation in honey bees (Apis mellifera, Apidae) to the conclusion from “Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility.” See also: Starfish reveal the origins of brain messenger molecules (February 9, 2016) One of the neuropeptides found is similar…

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An evolutionary theory killer

Subatomic: From thermophiles to humans (2)

February 10, 2018
James Kohl
RNA Directed, Subatomic
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Summary: As more information about natural selection for energy-dependent codon optimality made it clear that food energy was essential for species survival, the theorists continued to refuse to use experimental evidence to support their claims about how mutations and natural selection could lead to the evolution of a new species. Now, the theorists are left with foolish claims, like this “…the universe simply is, without ultimate cause or explanation.” Why Is There Something, Rather Than Nothing? by Sean M. Carroll…

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For God and Country

Kinetically Stable Thermodynamically Activated Cell Metabolism (4)

December 25, 2017
James Kohl
RNA Directed
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Experience-dependent pauses link the de novo creation of enzymes to the de novo creation of G protein-coupled receptors that link olfaction and the visual integration of other sensory input. That fact has been placed into the context of the “hard-problem” of consciousness. See: What makes mosquitoes attracted to Platanthera orchids? Delivering pulses of specific chemicals (EAGs) to the mosquitoes also provided a better understanding of the way orchids attract and use the mosquitoes to get pollinated. Interspecific differences among orchid…

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