pre-mRNA

Order and disorder: Ecological adaptations not mutations

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In the context of order and disorder that includes what is known about quantum physics and light-induced amino acid substitutions in plants and animals, as well as the control of the functional rearrangement of influenza hemagglutinin, I’m beginning to see even more confusion/obfuscation enter the picture of biophysically-constrained ecological adaptations. The nutrient-dependent ecological adaptations are now … Order and disorder: Ecological adaptations not mutations

microRNAs and species relationships

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Flaws emerge in RNA method to build tree of life Study finds problems with alluringly simple way to tease out evolutionary relationships through microRNA. Amy Maxmen 28 July 2014 Excerpt 1:  “…some pieces of RNA are only expressed at particular moments in an animal’s lifetime, whereas genes in the genome are steady.” Excerpt 2): “…microRNAs … microRNAs and species relationships

Cell-type differentiation

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How Do You Know When You’ve Found Them All? A Question That Applies To Beetles and Cancer Genes Alike by Carl Zimmer Conclusion: “Cancer biologists and beetle experts are not all that different when you think about it. They walk the same foggy road together, a long way from the end.” My comment: Only the cancer biologists … Cell-type differentiation

96 fixed amino acid substitutions, not 96 genes

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19 December, 2013 – 09:31 april holloway Entire Neanderthal genome finally mapped – with amazing results Excerpt (with my emphasis): “Only 96 genes responsible for making proteins in cells are different between modern humans and Neanderthals. Intriguingly, some of the gene differences involve ones involved in both immune responses and the development of brain cells in people.” “Somewhere within … 96 fixed amino acid substitutions, not 96 genes

Pheromones and cancer

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Transcription Factor-MicroRNA-Target Gene Networks Associated with Ovarian Cancer Survival and Recurrence Excerpt: “MicroRNAs (miRNAs) are small, non-coding RNA molecules that bind to complementary sequences on target mRNA transcripts, and thus, regulate gene expression at the post-transcription stage. Transcription factors (TFs) are a different type of regulator. These proteins bind to specific DNA sequences in the … Pheromones and cancer