protein folding chemistry

MicroRNA-mediated denuclearization

Kim Says North Korea Is Stopping Nuclear and Missile Tests Early today, he said the country was stopping nuclear and missile tests and shuttering its atomic test site, which has “done its job.” Those concessions were long demanded by the U.S., lifting hopes that next Friday’s planned summit between Kim and South Korean President Moon Jae-in will be conducted in good faith. Added Perspective Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies…

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Your indifference is killing you and others

Summary: Coherence-inducing mechanisms is double-speak for mechanisms that are nutrient-dependent and pheromone-controlled. Feedback loops link odor and pheromone signaling with reproduction has been presented in double-speak as Looplessness in networks is linked to trophic coherence We are currently studying the entropy of the coherence ensemble we defined for this work. “In general, higher trophic coherence would be associated with lower entropy states, which means that if networks are more coherent than the random expectation there must indeed be some kind…

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Feng Zhang refutes theistic evolution

Nucleic acid detection with CRISPR-Cas13a/C2c2 My summary: Their ability to detect single base differences links differences in the energy of photons to the light-induced de novo creation of RNA and to RNA-mediated amino acid substitutions that differentiate all cell types in all individuals of all living genera. Any claims about mutations and evolution have already been replaced by what serious scientists have learned about natural selection for energy-dependent codon optimality and the pheromone-controlled physiology of reproduction, which biophysically constrains all…

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Synthetic RNA-based switches

Synthetic RNA-based switches for mammalian gene expression control Current Opinion in Biotechnology, Volume 48, December 2017, Pages 54–60 If you wait until December, 2017 to see this article in print, you will probably be among the last of those to have missed a two decades-old paradigm shift. The fact that these researchers created synthetic RNA-based switches attests to the fact that natural selection for energy-dependent codon optimality links what organisms eat to energy-dependent RNA-mediated amino acid substitutions. The substitutions help…

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Thinking about energy is not radical re-thinking

The brain: a radical rethink is needed to understand it …Optogenetics, a technique that uses genetic modification of neurons so that their electrical activity can be controlled with light pulses – can help us to explore their specific contribution to brain function. Optogenetics links the speed of light on contact with water to what is known about all energy-dependent cell type differentiation in all individuals of all living genera. Serious scientists, for example, have linked angstroms to ecosystems in all living…

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Energy-dependent allelic imbalances, viruses, and pathology

Energy as information and constrained endogenous RNA interference poster presentation February 15, 2017 KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer February 23, 2017 These studies demonstrate that serial genetic changes at the Kras/KRAS locus are frequent in cancer and modulate competitive fitness and MEK dependency. Reported as: Genetic ‘balance’ may influence response to cancer treatment Taylor developed mathematical algorithms and software to analyze relative dosage of mutant KRAS and normal KRAS in tumor cells from…

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Theistic evolutionists fight back and lose (2)

For a historical perspective on the amount of ignorance theistic evolutionists and atheists have repeatedly displayed as they ignored everything known about the energy-dependent RNA-mediated de novo creation of genes, see: The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (1982) Thirty-five years later, there is another clear indication that theorists and atheists will never consider the fact that there must be an anti-entropic virucidal source of energy. See for example: HSP90 Shapes the Consequences of…

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Bill Gates refutes theistic evolution (prequel)

On February 22, 2017, self-proclaimed fitness expert Amir Siddiqui, wrote: James Kohl you didn’t predict jack ____ See my predictions in the context of: Search Results for “”virus-driven energy theft”” See also: RNA editing refutes theistic evolution See also:  Plague! How to prepare for the next pandemic …the world now has an emergency medical response team – which, astonishingly, it never had before. Pardis Sabeti may still be part of the response team, and most of them still may not…

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Francis S. Collins refutes theistic evolution

Criticisms of the nutrient-dependent pheromone-controlled evolutionary model Based on his writings, both published and unpublished, James Kohl presents an unsupported challenge to modern evolutionary theory and misrepresentations of established scientific terms and others’ research. — Andrew Jones, BA Editor’s note The 2013 review article by James Vaughn Kohl published in Socioaffective Neuroscience & Psychology and criticized in the above Letter to the Editor was subjected to standard peer review and the revised version was accepted by me after it had…

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