This View of Life: Completing the Darwinian Revolution (2/26/19) Review submitted [2/26/19 at 10:10 am]- Thank you! We’re processing your review. This may take several days, so we appreciate your patience. We’ll notify you when this is complete. He places neo-Darwinian evolution back into the context of ecological adaptations You must read between the lines … DS Wilson’s view of biophysically constrained life (2)
Transcription drives DNA replication initiation and termination in human cells …although origins have been observed via several independent techniques to be enriched close to transcribed genes and a range of other chromatin features (Besnard et al., 2012; Dellino et al., 2013; Langley et al., 2016; Petryk et al., 2016), a coherent model that encompasses both … Emergence of a coherent model
A pathway for mitotic chromosome formation The combination of nested loops distributed around a helically twisted axis plus dense chromatin packing achieves the 10,000-fold compaction of chromatin into linearly organized chromosomes that is required for accurate chromosome segregation when cells divide. The compaction of chromatin in the context of hydrophobicity is the topic of: Structural … A reversible TCA cycle in a thermophile (3)
Summary: Coherence-inducing mechanisms is double-speak for mechanisms that are nutrient-dependent and pheromone-controlled. Feedback loops link odor and pheromone signaling with reproduction has been presented in double-speak as Looplessness in networks is linked to trophic coherence We are currently studying the entropy of the coherence ensemble we defined for this work. “In general, higher trophic coherence … Your indifference is killing you and others
Summary: The “… universal applicability for determination of various targets such as metal ions, miRNAs, DNAs and proteins…” is the key to understanding the differences in the energy-dependent assembly of cell types with fixed amino acid substitutions that link natural selection for energy-dependent changes in base pairs from atoms to ecosystems in all living genera. … Measuring energy vs human idiocy (social science)
The brain: a radical rethink is needed to understand it …Optogenetics, a technique that uses genetic modification of neurons so that their electrical activity can be controlled with light pulses – can help us to explore their specific contribution to brain function. Optogenetics links the speed of light on contact with water to what is known … Thinking about energy is not radical re-thinking
For a historical perspective on the amount of ignorance theistic evolutionists and atheists have repeatedly displayed as they ignored everything known about the energy-dependent RNA-mediated de novo creation of genes, see: The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (1982) Thirty-five years later, there is another clear indication that theorists … Theistic evolutionists fight back and lose (2)
See: Dobzhansky 1973 and precision medicine (3) Evidence-based medicine has been hijacked: a report to David Sackett Fake news See for comparison: Sugar Gliders, Flying Squirrels, and How Evolutionists Explain Away Uncooperative Data …contradictory evidence drives evolutionists to embrace irrational just-so stories. Natural selection cannot “adapt” anything. Natural selection kills off the bad designs. It … Dobzhansky 1973 and precision medicine (4)
Is there any other holiday in the world that celebrates biophysically constrained cell type differentiation in all living genera? The availability of amino acids and proteins in new genes is nutrient energy-dependent. The de novo creation of genes is biophysically constrained by the innate immune system and the physiology of reproduction. That fact was detailed … Happy biophysically constrained Thanksgiving (in the USA)
Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of … Polycombic ecological adaptation as a science, not a theory (2)
