RNA-Mediated

See first: Natural selection for adaptation (10) DNA Logic Circuits for Multiple Tumor Cells Identification Using Intracellular MicroRNA Molecular Bispecific Recognition 9/5/21 The bispecific intracellular miRNA controllable DNA circuit…easily extends to various cell type discrimination by adjusting the [energy-dependent biophysically constrained Creation of] miRNA species… When Fauci claimed it was molecularly impossible to engineer SARS-CoV-2 in the Wuhan lab, the extent of his lies became clear. The fact that he lied before Congress is now clearer. See: Learning noncoding RNA…

Natural selection for adaptation (10)

September 7, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

See: Ignoring light-activated microRNA biogenesis 10/16/18, and compare our section on pre-mRNAs and molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996) to MicroRNAs buffer genetic variation at specific temperatures during embryonic development 10/16/18, which was previously published sans mention of microRNAs as Temporal development of Drosophila embryos is highly robust across a wide temperature range 7/11/18 Changing the term from pre-mRNAs to microRNAs obfuscated food energy-dependent pheromone-regulated genetic processes of cause and effect, but see ~127,000 indexed publications…

Natural selection for adaptation (9)

September 7, 2021

Adaptations, Diseases & Disorders, Ecology, microRNA editing, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity

“Mapping the dynamic transfer functions of eukaryotic gene regulation” 8/31/21 links energy-dependent changes from angstroms to ecosystems via “Sterically confined rearrangements of SARS-CoV-2 Spike protein control cell invasion“ For review see Lynn Zechiedrich‘s group: “Structural diversity of supercoiled DNA” and the representation of God’s Creation of energy-dependent microRNA-mediated biodiversity in: See also: Chemists Know (10/6/14) Remember to start with Feynman’s claims about food energy. Stop the killing spree! Protect yourself sans synthetic mRNA vaccine-induced pathology. See also: Getting Closer to…

MicroRNA-mediated population control (9)

August 13, 2021

Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA interference, What's in the News

See first: MicroRNA-mediated population control (8) 8/6/21 Light-activated microRNA biogenesis and peptide synthesis at the origin of life link biophysical constraints on the 2nd Law of thermodynamics to microRNA-mediated biophysically constrained viral latency in all model organisms. Added support for the facts were published on 8/11/21. See: Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients The facts were reported as: Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication…

microRNA-mediated election cycles (7)

July 15, 2021

Adaptations, base editing, Diseases & Disorders, Ecology, microRNA editing, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic

Are multi-quasiparticle interactions important in molecular ionization? 3/28/21 GWΓ [calculations] offers a unified description across all relevant energy scales. Our results suggest that the multi-QP regime corresponds to dynamical correlations, which can be described via perturbation theory. Few intelligent serious scientists understand the complexities of calculations needed to link God’s Creation of energy-as- information to biophysically constrained viral latency and healthy longevity across kingdoms. Most of them know what happens when a paradigm fails. Pseudoscientists know when they got stuck…

microRNA-mediated replication cycles (10)

July 7, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, Subatomic, Variations

See first: microRNA-mediated replication cycles (9) Conclusion from Guenther Witzany What is Life? 3/18/20 …new nucleotide sequences now appear to have originated from social agents such as viruses, their parasitic relatives, and related RNA networks, not from errors. A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative. The twentieth century narrative led to curated news reports that favored stupid…

microRNA-mediated replication timing (5)

July 2, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

Facts about energy-dependent microRNA-mediated biophysical constraints, which link protonated RNA interference (RNAi) to cell type differentiation across kingdoms via the physiology of reproduction and fixation of amino acid substitutions in organized genomes, are included in: pre-mRNA spatial distributions suggest that splicing can occur post-transcriptionally 6/29/21 Our results suggest a model in which transcription and splicing are largely independent, and the existence of a slow moving zone around the transcription site allows for the unification of co-transcriptional and post-transcriptional models of…

microRNA-mediated replication timing (1)

June 17, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity

2 Comments

The phylogenetic utility and functional constraint of microRNA flanking sequences links the patent for naturally occurring light-activated carbon fixation to viral latency and healthy longevity across kingdoms. The patent: RNA-Guided Human Genome Engineering was linked from functional constraints to gain-of-function research in High-Quality Overlapping Paired-End Reads for the Detection of A-to-I Editing on Small RNA WHO failed to examine the problems associated with gain-of-function research, which researchers now suggest led to the creation of SARs-CoV-2. The creation of SARs-CoV-2 can be…

Quantum Darwinism (9)

April 19, 2021

Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity

Beyond the Elements: Life (video with transcript) There was a turning point, the evolution of a transformative series of chemical reactions that, over time, remade the planet… They place God’s Creation of sunlight and humidity at the origin of life (THE turning point) into the context of experimental evidence of enzyme-dependent directed evolution, which requires this stupid assumption from 2005. “Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.” Enzymes are proteins. No experimental evidence of…

Quantum Darwinism (5)

April 15, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic