replication

Defeating Disease and Communism (2)

On 4/23/20 former President Donald J. Trump reportedly linked God’s Creation of sunlight and humidity to the energy-dependent weakening of coronaviruses via RNA–RNA interaction between host and virus, but see Experts say there’s no medical basis for Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/24/20 Jonathan Reiner, professor of medicine at The George Washington Defeating Disease and Communism (2)

Defeating Disease and Communism (1)

Defeating Diseases with Energy 1/9/18 The mitochondria turn food’s hydrogen and carbon and inhaled oxygen into carbon dioxide (CO2), water and adenosine triphosphate, or ATP, which stores energy. God’s ATP-dependent Creation of RNA links protonated RNA interference to healthy longevity. See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and Defeating Disease and Communism (1)

Loss of energy as information (1)

Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I Loss of energy as information (1)

Cryo-EM: More than a suggestion

Cryo-EM imaging suggests how the double helix separates during replication October 23, 2017   Details in the structure not previously seen reveal how various protein subunits of the twin hexamers latch on to the double helix, via tiny loop-like structures. What are the subunits of protein? The subunits of proteins are called amino acids. I Cryo-EM: More than a suggestion

Entertaining yourself to death

Lethal virus kills 5 billion people?

Summary: Food energy is required for the creation of enzymes that metabolize the food, which links the metabolism to the pheromone-controlled physiology of reproduction in species from microbes to humans via alternative splicings of pre-mRNAs, which are now called microRNAs in more than 65,000 published works. The horrid tradjedy of of yet another preventable death Entertaining yourself to death

Coulombic interactions facilitate polycombic adaptation

RNA Structural Modules Control the Rate and Pathway of RNA Folding and Assembly Summary: Everything known to serious scientists about energy-dependent biophysically constrained RNA-mediated protein folding chemistry is attributed to “Nature” and evolution with no consideration for where the energy came from or where it goes when viruses use it for their replication. See also: Coulombic interactions facilitate polycombic adaptation

Polycombic ecological adaptation as a science, not a theory (2)

Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of Polycombic ecological adaptation as a science, not a theory (2)

RNA methylation, learning, memory and behavior,

Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice    Excerpt: Our findings suggest that m6A is regulated in an activity-dependent manner in the adult brain, and may function to fine-tune mRNA turnover during memory-related processes.   My comment: They cite: Alarcón CR, Lee H, Goodarzi H, Halberg N, RNA methylation, learning, memory and behavior,

Olfaction & the octopus and human genomes (2)

Darwinian evolution in the light of genomics Eugene Koonin excerpt: The distribution of evolutionary rates across sets of orthologous genes, the distribution of the sizes of paralogous gene families, the negative correlation between the expression level and the sequence evolution rate of a gene, and other relationships between key evolutionary and phenomic variables seem to Olfaction & the octopus and human genomes (2)

Faithfully repaired DNA

Origin and Evolution of DNA and DNA Replication Machineries Excerpt: …DNA replaced RNA as genetic material because it is more stable and can be repaired more faithfully.4 My comment: RNA-mediated amino acid-dependent DNA repair is nutrient-dependent. That fact need not be taken “on faith.” Without DNA repair, ecological variation could not be linked to ecological adaptations Faithfully repaired DNA