reproduction

Virus-driven downsizing of the human brain (4)

April 23, 2017
James Kohl
Adaptations, Ecology, Human Pheromones, Model Organisms, Variations
One Comment

Virus-driven downsizing of the human brain (7/1/16) Virus-driven downsizing of the human brain (2) (7/6/16) Virus-driven downsizing of the human brain (3) (8/9/16) Excerpt: A Postdoctoral Researcher threatened me with litigation if I did not remove the tags with his name that linked his works to works at the institution where he works. In an attempt to discuss Breakthrough in understanding how stem cells become specialized More than two years ago, he wrote: We house our animal mouse models in…

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Physicists: Desperate Acts (revisited)

February 6, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, Variations
One Comment

Physicists: Desperate Acts Light-induced endogenous RNA interference in bioluminescent microbes links Schrodinger’s claims in “What is LIfe?” (1944) from a light-to-chemical pathway of information exchange in all living genera via amino acid substitutions in supercoiled DNA. All subsequent works on the evolutionary synthesis failed to link  the anti-entropic virucidal energy of sunlight to Darwin’s “conditions of life” from the claims of Schrodinger (1944) or the claims of any other serious scientist. Indeed, in the case of higher animals we know…

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Dobzhansky 1973 and precision medicine

January 19, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
3 Comments

MicroRNA-34 directly targets pair-rule genes and cytoskeleton component in the honey bee Our findings point to miR-34-5p as novel regulatory component in the complex molecular cascade that governs insect segmentation and to a broader role of miRNAs in the early development due to the detection of mature transcripts from both 5p and 3p arms for several precursor miRNAs. Thus, this work encourages further investigation to pinpoint miRNAs as fine tuners of insect early development. Anna Di Cosmo‘s group took the…

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Science journalists or paid propagandists? (2)

January 8, 2017
James Kohl
Adaptations, Ecology, Model Organisms, RNA Directed, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
One Comment

See: Science journalists or paid propagandists? Excerpt: Riffell is interested in how chemical signals, like smells, affect behavior. Explore further: Researchers show that the mosquito smells, before it sees, a host. This was reported last year in “Science” and on January 6, 2017 as Orchids mimic human body odor to attract mosquitoes The year-long delay aroused my suspicion because everything known to serious scientists since 1996 has linked food odors and pheromones to reproduction in species from microbes to humans.…

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Science journalists or paid propagandists?

January 8, 2017
James Kohl
Adaptations, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA-mediated epigenetic regulation of gene expression
One Comment

2016 Orchids give off human ‘body odor’ to attract mosquitoes See also: Beatriz Moisset • a year ago Were humans present in the orchid’s habitat long enough and often enough for this coevolution to take place? More likely, other animals emit the same body odors as humans. There should be a mention of this. See also: SICB Annual Meeting 2017 The 2017 SICB conference report by Pennisi may be pending. Hopefully, a 2017 conference report from at least one ethical…

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Energy-dependent alternative splicings 1996 – 2016 (2)

December 31, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, Ecology, Model Organisms, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

See also: Energy-dependent alternative splicings 1996 – 2016 Re: Rs3827760 is Val370Ala and EDARV370A No matter what it is called, Val370Ala may be the best example of how nutrient energy-dependent biophysically constrained pheromone-controlled viral latency protects all organisms from virus-driven energy theft and all pathology. For example, see: Genome recoding by tRNA modifications The succession of mRNA codons controls the synthesis of polypeptides through the complementarity between each of the 64 possible codon triplets and the tRNA anticodons that decode…

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Energy-dependent alternative splicings 1996 – 2016

December 26, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

Highlights: 1) Alternative splicings of messenger RNA link the sun’s anti-entropic virucidal energy as information to DNA repair. 2) DNA repair links fixation of amino acid substitutions in supercoiled DNA to healthy longevity. 3) Supercoiled DNA protects all organized genomes from virus-driven energy theft and genomic entropy. 4) Genomic entropy is less likely to occur in the context of the physiology of reproduction and transgenerational epigenetic inheritance of ecologically adapted morphological and behavioral phenotypes. 5) Preventing virus-driven energy theft from…

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Energy-dependent self-organization and self repair

December 13, 2016
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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Energy-dependent autophagy links food odors and pheromones from the innate immune system and RNA-mediated feedback loops to the physiology of reproduction in all living genera via chromosomal inheritance. Transgenerational epigenetic inheritance is nutrient-energy-dependent and pheromone-controlled. That fact has been established in the extant literature since 1933, when Thomas Hunt Morgan won the Nobel Prize in Medicine, and Erwin Schrodinger shared the 1933 Prize in Physics with Paul A.M. Dirac. See for example: From Fertilization to Adult Sexual Behavior December 1996…

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Autophagy is the antiphage defense strategy

December 8, 2016
James Kohl
Autophagy, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
3 Comments

The “Antiphage Defense Strategy” in Vibrio anguillarum is called autophagy by many serious scientists. It links nutrient energy-dependent pheromone-controlled quorum sensing to viral latency, healthy longevity, symbiosis, reproduction, and biodiversity from microbial species to humans. For an evolutionary approach to energy-dependent autophagy that fails to address any aspect of how virus-driven energy theft causes all pathology see: (12/7/16) Part I: Living together: The symbiosis of host-microbial interactions (12/7/16) See also: 12/7/16 ….McFall-Ngai tells the story of a symbiosis between the…

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