Richard Feynman

Naturally attenuated viral endemicity (6)

November 24, 2021
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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See first: Naturally attenuated viral endemicity (5) 11/15/21 Blog post # 1600 is based on a search for microRNA that returns 130,538 items There are now 130,965 results. This was added on 11/23/21 Insights into Health-Promoting Effects of Plant MicroRNAs: A Review The authors link God’s Creation of energy-as-information to light-activated microRNA biogenesis in plants. The signalling pathways link the ATP-dependent creation of RNA and the pheromone-regulated genetic processes of reproduction in species from cyanobacteria to humans. Naturally occurring light-activated…

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Odor activation of ATP (2)

March 26, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, Subatomic
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Metabolic Regulation of Cytoplasmic DNA Synthesis (1974) The curve that results when the rate of DNA synthesis is plotted as a function of ATP concentration is sigmoidal, suggesting that more than one site on the enzyme interacts with ATP and that these sites are acting cooperatively. Odor activation of ATP is the obvious link to RNA-mediated feedback loops that control the food energy-dependent pheromone-controlled physiology of reproduction via the rate of DNA repair in species from microbes to humans. See:…

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Two retractions of human idiocy

December 7, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Excerpt: …she was interested in the PNAS research because it identified a potential inhibitor of the hepatitis C virus… ”Definitely embarrassing:” Nobel Laureate retracts non-reproducible paper in Nature journal 1) This retraction marks the second in six months for Nature Chemistry after having none for eight years. 2) In 2009, Szostak also retracted a 2008 paper in Proceedings of the National Academy of Sciences after an outside researcher could not replicate the results. The retraction notice credited Katherine Berry, then…

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Loss of energy as information (1)

October 24, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I think Koonin may be attempting to address the concerns brought forward after another biologically uninformed science idiot claimed that my refutation of neo-Darwinian pseudoscientific nonsense…

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Criticisms of a validated model

October 4, 2017
James Kohl
base editing, RNA Directed, RNA editing, RNA-directed DNA methylation
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Microglia Turnover in the Human Brain “With electron microscopy, we find a variety of immune cells in the brain, especially in contexts of disease,” she writes. Richard Feynman predicted this in the context of a lecture on nanotechnology. He presciently placed cryo-EM into the context of a lecture about Plenty of Room at the Bottom. Examination at this level of observable energy-dependent top-down causation has since linked the sun’s anti-entropic virucidal energy from hydrogen-atom transfer in DNA base pairs in…

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Predicting who wins the 2017 Nobel Prizes (5)

October 3, 2017
James Kohl
Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, Subatomic
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Summary: If he was not still dead, the 1965 Nobel Laureate, Richard P. Feynman might claim that this year’s Physics Prize was awarded for “human idiocy.” Nobel Prize in Physics Awarded to LIGO Black Hole Researchers Einstein’s General Theory of Relativity, pronounced in 1916, suggested that matter and energy would warp the geometry of space-time the way a heavy sleeper sags a mattress, producing the effect we call gravity. His equations described a universe in which space and time were…

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Sexual communication signals: New Insights!

August 31, 2017
James Kohl
Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, Subatomic
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Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull New insights in the evolution of sexual communication signals Abstract excerpt: Our research focuses on identifying a) the genes underlying sexual signals and responses in both sexes2-4, and b) ecological factors that may cause divergence in…

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Energy-dependent physical and biophysical constraints (5)

July 26, 2017
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, Variations
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Summary: Emmy Noethe’s theorems were developed in the early 1900’s. Richard Feynman inadvertently or purposefully alluded to them as examples of human idiocy. Discover Magazine resurrected the examples of human idiocy in a 2017 article. For comparison, Choi et al., (2017) support the claims that intercellular and interkingdom communication is energy-dependent and controlled by the metabolism of food energy to pheromones. It is obvious that pheromones biophysically constrain the virus-driven degradation of messenger RNA. That fact links everything currently known…

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Energy-dependent physical and biophysical constraints (2)

July 25, 2017
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
One Comment

Summary: The mind does not exist in nature. It is a manifestation of how ecological variation must be linked to the creation of food energy-dependent pheromone-controlled ecological adaptations. Energy-dependent physical and biophysical constraints (1) The energy-dependent de novo creation of all receptors is biophysically constrained. See: Channel opening and gating mechanism in AMPA-subtype glutamate receptors This was reported as: Scientists capture first image of major brain receptor in action Defects in glutamate receptors, or the processes they mediate, are implicated…

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God’s shrinking role in salvation

June 13, 2017
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations
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God’s shrinking role in salvation can temporarily be placed into the context of what serious scientists are reporting for comparison to the claims of pseudoscientists. See: Quantum Simulation (free download) It presents several examples of experiments using both density and momentum imaging and quantum gas microscopy to study the motion of atoms in optical lattices. The energy-dependent motion of atoms must be linked to ecosystems by the physiology of pheromone-controlled reproduction in all living genera. That fact requires extended consideration…

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