RNA editing

Energy-dependent purifying selection / autophagy (6)

See: Energy-dependent purifying selection / autophagy (5) Simply put all aspects of biophysically constrained energy-dependent cell type differentiation must first be linked from the physiology of reproduction to ecological adaptations, or they must be linked from energy theft to the evolution of pathology. See for contrast and comparsion: Finding your diagnosis in the brave new Energy-dependent purifying selection / autophagy (6)

DNA repair via junk DNA (2)

See also: DNA repair via junk DNA (1) Recently Evolved Genes Identified From Drosophila yakuba and D. erecta Accessory Gland Expressed Sequence Tags (2006) Reported in Singer (2015) as: In 2006, Begun found some of the first evidence that genes could indeed pop into existence from noncoding DNA. Singer’s claim that genes automagically pop into DNA repair via junk DNA (2)

The radical pair mechanism of ecological speciation

The radical pair mechanism and the avian chemical compass: Quantum coherence and entanglement Excerpt: Radical pairs are usually produced as short-lived intermediates through decomposition, electron transfer, or hydrogen transfer reactions from singlet or triplet excited states. My comment: The radical pair mechanism appears to be another link from nutrient energy-dependent hydrogen-atom transfer in DNA base pairs The radical pair mechanism of ecological speciation

Finding peace and π in the light of H bond energy

It might be amusing if the misrepresentations of links between energy and cell type differentiation by people like PZ Myers were not going to cause more suffering and death.  Instead, two years after his attack on me for my accurate representations of the link from nutrient energy-dependent chromosomal rearrangements to pheromone-controlled biodiversity in species from Finding peace and π in the light of H bond energy

Virucidal effects on ecological speciation

An Adaptor Hierarchy Regulates Proteolysis during a Bacterial Cell Cycle Abstract excerpt: …additional factors are inexplicably required for cell-cycle-dependent proteolysis. Here, we show that these factors constitute an adaptor hierarchy wherein different substrates are destroyed based on the degree of adaptor assembly. Abstract conclusion: Our work reveals how hierarchical adaptors and primed proteases orchestrate regulated Virucidal effects on ecological speciation

Protein isoforms do not evolve

This Is My Vision Of “Life” A Conversation With Richard Dawkins [4.30.15] Introduction by: John Brockman Excerpt: Through the amazing set of posttranscriptional mRNA processing mechanisms uncovered in the last 40 years (including alternative splicing and RNA editing), transcription of a single gene often results in the production of many distinct protein isoforms with very Protein isoforms do not evolve

Reverse phosphorylation

See for review: Let there be anti-entropic light (1)   Squid are hyper-editors when it comes to RNA This is a great summary of what is currently known about anti-entropic light and nutrient-dependent RNA-mediated pheromone-controlled cell type differentiation. Excerpt: “During RNA editing, specific enzymes alter nucleotides in mRNA transcripts so that the resulting protein differs Reverse phosphorylation

RNA-protein interactions reveal biophysical to ecological landscapes

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes RNA-protein interactions are tethered to DNA via ultra-high-throughput measurement of the RNA-protein interactions that link amino acid substitutions to cell type differentiation. Differences in affinity are often driven by sequence-specific changes in both association and dissociation rates that rapidly link RNA-protein interactions reveal biophysical to ecological landscapes

Intelligent viruses and cancers?

The Very Intelligent Ebola Virus Takes Front and Center Excerpt 1) “Ebola doesn’t enter the nucleus. It uses the cell’s machinery of ribosomes and transfer RNA to make proteins from the viral messengerRNA.” Excerpt 2) “Normally, mechanisms inside the nucleus have complex relations with messenger RNA and the alternative RNA editing process (see RNA alternative Intelligent viruses and cancers?