RNA interference

Bruce McEwen’s legacy: sympatric speciation (3)

Recent additions to the available information on energy-dependent microRNA-mediated cause and effect can be found in:  Bruce S. McEwen’s legacy: sympatric speciation (2) Moving forward: On the day after Bruce S. McEwen died, the preprint for Integrated analysis of directly captured microRNA targets reveals the impact of microRNAs on mammalian transcriptome 6/15/19 was published in Bruce McEwen’s legacy: sympatric speciation (3)

A microRNA-mediated healthy New Year! Thank God (2)

MicroRNA-mediated suppression of P-glycoprotein by quantum dots in lung cancer cells 12/27/19 The interactions between adenosine triphosphate‐binding cassette (ABC) transporters and nano‐sized materials are attracting increasing attention, due to their great potential in overcoming the multidrug resistance (MDR) phenomena in cancer treatment. Adenosine triphosphate (ATP) is a complex organic chemical that provides energy to drive A microRNA-mediated healthy New Year! Thank God (2)

Light-activated PTEN-dependent viral latency (2)

See first: Light-activated PTEN-dependent viral latency (1) 12/25/19 On 12/26/19, Cold Spring Harbor Laboratory responded to my accurate representations of light-activated energy-dependent biophysically constrained viral latency with a report on Biophysical models of cis-regulation as interpretable neural networks 11/8/19 See: Finally, machine learning interprets gene regulation clearly 12/26/19 “…understanding how something like gene regulation works—is Light-activated PTEN-dependent viral latency (2)

microRNAs Constrain Virus-driven Pathology (3)

8 hours, 1125 Impressions and 21 engagements may not be the key to healthy longevity. But, President Donald J. Trump’s scientific advisor KB Whaley, and other serious scientists, will ensure the change from claims about mutation-driven evolution to facts about energy-dependent phosphorylation and RNA interference. The facts about naturally occurring light-activated carbon fixation and protection microRNAs Constrain Virus-driven Pathology (3)

MicroRNA-mediated hypoxia vs cancer (2)

Viruses in anaerobic bacteria thrive via replication in hypoxic conditions. Oxygen helps to biophysically constrain viral replication in aerobic bacteria. Oxygen does not create itself. The Creation of sunlight and water (Darwin’s “conditions of life”) come before the Creation of oxygen, which typically biophysically constrains nearly all pathology in the context of RNA interference. See:  MicroRNA-mediated hypoxia vs cancer (2)

#SFN2019 to 2012: Hiding the facts (1)

From Fertilization to Adult Sexual Behavior (1996) Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans… That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from #SFN2019 to 2012: Hiding the facts (1)

Chemogenetic kinetics (2): Extinction

Biologically uninformed theorists failed to link light-activated energy-dependent “conditions of life” to biophysically constrained viral latency. That led them to ignore the consequences of virus-driven degradation of messenger RNA in species from microbes to humans. Their ignorance led to recent claims about the discovery of a model, which places Charles Darwin’s prescient claims about natural Chemogenetic kinetics (2): Extinction

Chemogenetic kinetics (1): Creation

Summary: The virus-driven theft of the sun’s anti-entropic energy, which is required for biophysically constrained cell type differentiation, causes the degradation of messenger RNA (mRNA). The degradation of mRNA links mutations to all pathology.  Fixation of energy-dependent RNA-mediated amino acid substitutions is the chemogenetic link from energy-dependent kinetics to single nucleotide polymorphisms (SNPs) and genetic Chemogenetic kinetics (1): Creation

Nutrient-dependent Pheromone-controlled cures (2)

See: Nutrient-dependent Pheromone-controlled cures (1) My summary: They linked one base pair and one amino acid in a light-assembled microRNA-RNA-peptide nanocomplex to protection from nutrient stress-linked and/or social stress-linked virus-driven degradation of messenger RNA, which links mutations to all pathology. Naturally occurring energy-dependent RNAi prevents all virus-driven diseases. On 8/26/19, a friend sent me an Nutrient-dependent Pheromone-controlled cures (2)

The tipping point (revisited) 90K (4)

Three recently published articles sow the seeds of discontent linked to the social media storm of complaints about celebrity pseudoscientist, Neil deGrasse Tyson. Could the Big Bang be Wrong? 6/15/19 New tactics clash on speed of expanding universe 7/26/19 Twitter slams Neil deGrasse Tyson for ‘tasteless’ tweet about mass shootings: ‘Lost all respect for you The tipping point (revisited) 90K (4)