RNA-mediated amino acid substitution

The tipping point (revisited): 73,000 publications

Summary: The Bill and Melinda Gates Foundation appears to be funding misrepresentations of what serious scientists know about biophysically constrained viral latency, as if no one knew that the effect of virus-driven energy theft in a computer processing unit (CPU) is the same as the effect of bacteriophages on the human brain. The countdown that led scientific creationists in South Korea to force the denuclearization of North Korea started 2 years ago (today). 5, 4, 3, 2, 1 Predicting microRNA-disease…

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Diet-driven RNA interference and mental health (3)

Discover’s “My Science Shop” now advertises the games that led to development of the cell biology game: “Cystosis,” which is a neo-Darwinian evolutionary theory-killer. Cytosis links the creation of anti-entropic viruidal light to all biodiversity on Earth via the physiology of reproduction and biophysically constrained viral latency. See the dumbed-down version of that fact: Missing Mutations Suggest a Reason for Sex Summary: A good model with a good model organism predicts. The mouse-to-human model of biophysically constrained viral latency predicts…

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BiondVax Universal Flu Vaccine Patent

Summary: …the dream to create an effective universal flu vaccine to ultimately eradicate the flu is placed into the context of claims about changes to the virus. The changes are energy-dependent ecological adaptations. No one claims that the virus mutates or that it evolves. Only biologically uninformed theorists make such ridiculous claims. BiondVax Universal Flu Vaccine Patent Granted in India The patent describes influenza vaccines comprised of multiple copies of several epitopes, such as M-001 which contains nine common and…

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The MicroRNAome Strikes Back: A Sokalian hoax (3)

One way to recognize a Sokalian hoax is to determine whether the claims can be linked from gravity or from the speed of light on contact with water to feedback loops that biophysically constrain viral latency and all biodiversity in all living genera. See: Feedback loops link odor and pheromone signaling with reproduction See for comparison: Chiromagnetic nanoparticles and gels Reported as: Nanoparticle gel controls twisted light with magnetism The trick, the researchers found, was to twist the nanoparticles themselves by coating them…

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Another failed attempt to address the malaria challenge

Malaria Vaccine Developed by Using Genetic Modifications We are very fortunate to have the human malaria challenge model to take the critical next step evaluating the efficacy of GAP3KO in preventing malaria in people… They are fortunate to be able to monetize their findings without mention of the facts already known about hemoglobin variants in hummingbirds and humans. My comment on the Labroots report: Hemoglobin S is the variant that links ecological variation from natural information processing and natural selection…

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Linking RNA structure to function

A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage was reported on September 8, 2016 as: Linking RNA structure and function Excerpt 1) Learning more about how lncRNAs control cell differentiation could offer a new approach to developing drugs for patients whose hearts have been damaged by cardiovascular disease, aging, or cancer. The insult to the intelligence of all serious scientists who have linked energy-dependent changes from angstroms to ecosystems in…

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Antithetical conclusions (6)

Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1 (Subscription required) Abstract excerpt: This structure also allowed for the mapping of cancer-causing mutations within the kinase domain, suggesting that a loss of kinase function may contribute to tumorigenesis. Continued See: Antithetical conclusions (5, 4, 3, 2) In the same issue of this journal, see: A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus (Subscription required) Abstract excerpt: We demonstrate that single-site alanine replacements of basic residues in…

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Energy-dependent RNA methylation (1)

“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?” — Roger Penrose “We know, for instance, when we eat food nucleic acids can get into our cells. Also, there is a theory that our cells in the body keep sending out nucleic acids and one theory has it that it seems to correct the mistakes that other cells have suffered…

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Selective reporting of inferences: examples of pseudoscience

In the narrative of this presentation on RNA mediated molecular epigenetics and virus driven entropy, I mentioned that Cori Bargmann is scheduled to deliver a lecture entitled “Genes, neurons, circuits and behavior: an integrated approach in a compact brain.” An integrated approach will help others understand what is currently known about how ecological variation leads to ecological adaptation. Works, like hers, with the nematode model organism will help others understand how ecological adaptation leads to biodiversity in the morphological phenotypes…

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