RNA SYNTHESIS

Coherently organized healthy longevity (1)

A large-scale binding and functional map of human RNA-binding proteins [RBPs] 7/29/20 We describe the spectrum of RBP binding throughout the transcriptome and the connections between these interactions and various aspects of RNA biology, including RNA stability, splicing regulation and RNA localization. These data expand the catalogue of functional elements encoded in the human genome by the addition of a large set of elements that function at the RNA level by interacting with RBPs. Reported as: ENCODE consortium identifies RNA…

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pH-dependent viral latency (6)

See first: pH-dependent viral latency (5) Researchers from Iran linked light-activated microRNA biogenesis in plants to the expression genes that effect the number, size and/or the pH of pathways that influence melanin synthesis in the context of human iris color and human skin pigmentation via the L‐tyrosine amino acid precursor. The claim on 6/5/20 by Frank M. LaFerla about the links from energy-dependent changes in microbes to humans and racism was retracted on the same day. Thank God, scientific Creationists…

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The tipping point (revisited): 100K (3)

More than 100,000 indexed published works that mention microRNAs link the Creation of anti-entropic virucial light from light-activated microRNA biogenesis to RNA-mediated autophagy via the physiology of reproduction and biophysically constrained viral latency in all living genera. See for review: The tipping point (revisited): 100K (1) at MicroRNA-mediated.pro See for review: The tipping point (revisited): 100K (2) at Autophagy.pro Moving forward to what is known about how microRNAs are linked from RNAs to healthy longevity see: Autophagy regulation by microRNAs:…

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NSF’s parrot and other parrots

Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) “Isolated thymus nuclei transport amino acids into an intranuclear pool by a process which seems to depend on energy from nuclear ATP synthesis (20).” The energy must be biophysically constrained: Long-range coherence and energy storage in biological systems (1968) Human Pheromones: Linking Neuroendocrinology and Ethology (revisited) (2010) Slide # 6 attests to the fact that the levels of biological organization…

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The MicroRNAome Strikes Back: A Sokalian hoax (9)

Summary: Darwin’s “conditions of life” link the creation of sunlight from the creation of ATP to the creation of microRNAs and RNA-mediated cell type differentiation in the context of biophysically constrained viral latency. There is no magical creation of an RNA force field or protein force field that could be used to link the magic of evolution to biologically-based diversity in species from microbes to humans. RNA force field with accuracy comparable to state-of-the-art protein force fields The complex and…

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Interethnic genetic similarities and differences (2)

From Massivesci.com Simulating evolution helped scientists design a better virus: It sounds like an arcane superpower. It boils down to random mutation and selection  January 9, 2018 See also: In an information ecosystem that grows ever more politically siloed, such lines of study are worth pursuing. January 11, 2018 Information ecosystems are energy-dependent. See: MicroRNA + cadherin The creation of adhesion proteins prevents genomic entropy. On January 11, 2018 Nadja (Chief Content Officer) from Massivesci.com wrote: We’re in the midst…

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A mental health problem at the highest level

Investigators look for clues in deadly church shooting – news – att.net Investigators look for clues in deadly church shooting – news – att.net Todd Piro reports from Sutherland Springs, Texas. …the result of a “mental health problem at the highest level.” The mental health problem is caused by the virus-driven degradation of messenger RNA, and by the ignorance of theorists who claim that mutations cause evolution. The theorists may not be intelligent enough to play the cell biology game…

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Exome Sequencing Impact in Routine Care

Summary: They placed the pseudoscientific nonsense about selection for beneficial mutations into the context of positive selection for mutations, which are caused by the virus-driven degradation of messenger RNA. The mutations have been linked to all pathology. It’s as if all theorists want to become known as “biologically uninformed science idiots” via their associations with others who have touted claims about “beneficial mutations.” US Air Force Studying Impact of Exome Sequencing in Routine Care Who, among my fellow veterans, and…

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Losers: rediscovering an epigenetic key

Epigenetic mechanisms modulate differences in Drosophila foraging behavior Little is known about how genetic variation and epigenetic marks interact to shape differences in behavior. Reported as: An epigenetic key to unlock behavior change October 16, 2017 “One of the big questions in the Child & Brain Development program over the years has been how experience gets embedded in our biology and the mechanisms for that,” says Sokolowski. See for comparison: See Brain on stress: How the social environment gets under…

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