RNA SYNTHESIS

microRNA-mediated election cycles (3)

See: microRNA-mediated election cycles (2) The most recent addition to the 124,062 indexed published works that mention ‘microRNA’ is A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine For background on this paradigm shift, see the following works: US Air Force Studying Impact of Exome Sequencing in Routine Care 10/19/17 The special considerations around fitness for duty and privacy make this a particularly challenging study to design and implement, but also an extremely important…

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microRNA-mediated replication timing (2)

Transcription typically requires the energy-dependent Creation of the enzyme RNA polymerase. Intelligent serious scientists know that enzymes do not automagically create themselves, and most of them realize that transcription began when God Created the anti-entropic virucidal energy of sunlight. The 6/4/21 cover of Science Magazine, places that fact about biophysically constrained transcription into the context of pH-dependent oxidative phosphorylation. However, McEwen et al’s claims from 1964 are not included in the content from “Structures of the human Mediator and Mediator-bound…

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Racist fascism vs individual liberty (1)

Racist fascists promote mask-wearing, social distancing, and mRNA vaccines despite the facts that link this so-called New perspective on the regulation of acetylcholinesterase via the aryl hydrocarbon receptor 12/5/20 to what is known about The Perfect Storm: COVID-19 Health Disparities in US Blacks 9/23/20 All intelligent serious scientists know that God’s Creation of hydrogen and water is required for His oxygen-dependent Creation of hydrocarbon receptors, which have now been linked to racial differences in COVID-19 health disparities. Thank God, members…

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Coherently organized healthy longevity (1)

A large-scale binding and functional map of human RNA-binding proteins [RBPs] 7/29/20 We describe the spectrum of RBP binding throughout the transcriptome and the connections between these interactions and various aspects of RNA biology, including RNA stability, splicing regulation and RNA localization. These data expand the catalogue of functional elements encoded in the human genome by the addition of a large set of elements that function at the RNA level by interacting with RBPs. Reported as: ENCODE consortium identifies RNA…

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pH-dependent viral latency (6)

See first: pH-dependent viral latency (5) Researchers from Iran linked light-activated microRNA biogenesis in plants to the expression genes that effect the number, size and/or the pH of pathways that influence melanin synthesis in the context of human iris color and human skin pigmentation via the L‐tyrosine amino acid precursor. The claim on 6/5/20 by Frank M. LaFerla about the links from energy-dependent changes in microbes to humans and racism was retracted on the same day. Thank God, scientific Creationists…

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The tipping point (revisited): 100K (3)

More than 100,000 indexed published works that mention microRNAs link the Creation of anti-entropic virucial light from light-activated microRNA biogenesis to RNA-mediated autophagy via the physiology of reproduction and biophysically constrained viral latency in all living genera. See for review: The tipping point (revisited): 100K (1) at MicroRNA-mediated.pro See for review: The tipping point (revisited): 100K (2) at Autophagy.pro Moving forward to what is known about how microRNAs are linked from RNAs to healthy longevity see: Autophagy regulation by microRNAs:…

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NSF’s parrot and other parrots

Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) “Isolated thymus nuclei transport amino acids into an intranuclear pool by a process which seems to depend on energy from nuclear ATP synthesis (20).” The energy must be biophysically constrained: Long-range coherence and energy storage in biological systems (1968) Human Pheromones: Linking Neuroendocrinology and Ethology (revisited) (2010) Slide # 6 attests to the fact that the levels of biological organization…

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The MicroRNAome Strikes Back: A Sokalian hoax (9)

Summary: Darwin’s “conditions of life” link the creation of sunlight from the creation of ATP to the creation of microRNAs and RNA-mediated cell type differentiation in the context of biophysically constrained viral latency. There is no magical creation of an RNA force field or protein force field that could be used to link the magic of evolution to biologically-based diversity in species from microbes to humans. RNA force field with accuracy comparable to state-of-the-art protein force fields The complex and…

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Interethnic genetic similarities and differences (2)

From Massivesci.com Simulating evolution helped scientists design a better virus: It sounds like an arcane superpower. It boils down to random mutation and selection  January 9, 2018 See also: In an information ecosystem that grows ever more politically siloed, such lines of study are worth pursuing. January 11, 2018 Information ecosystems are energy-dependent. See: MicroRNA + cadherin The creation of adhesion proteins prevents genomic entropy. On January 11, 2018 Nadja (Chief Content Officer) from Massivesci.com wrote: We’re in the midst…

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