RNA-triggered gene silencing.

ATP-dependent creation of RNA

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing They suggest that deep evolution somehow conserved energy-dependent phosphorylation sites. The sites somehow link changes in the microRNA/messenger RNA balance from RNA-mediated cell type differentiation to morphological and behavioral diversity via amino acid substitutions in supercoiled DNA. But they do not mention chirality, autophagy, or supercoiled DNA in ATP-dependent creation of RNA