Roger Penrose

MicroRNA-mediated alternative splicing (revisited)

Building one molecule from a reservoir of two atoms reported as: Cold chemistry with two atoms. They linked differences in the energy of photons from two different wavelengths of light, 700 nm and 976 nm, to the creation of the molecule NaCs*. They were able to detect molecule formation in the context of atom loss and NaCs* vibrational levels near the dissociation threshold. Detecting resonances that have not been previously observed appears to be the link from quantum physics to…

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Cell type assembly and the space-time continuum

Summary: The time to adopt energy-dependent cell type assembly as the unit of cognition was in 1944, when Schrodinger published “What is Life.” By the time Roger Penrose made his comment in the reprint edition, everyone else was too late. Penrose wrote: “How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?” (Roger Penrose 8 August 1991) See: Time (and space)…

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Epigenetic effects of stress by Bruce McEwen (1)

A rendering of how changes in an electron’s motion (bottom view) alter the scattering of light (top view), as measured in a new experiment that scattered more than 500 photons of light from a single electron. Previous experiments had managed to scatter no more than a few photons at a time. Credit: Extreme Light Laboratory|University of Nebraska-Lincoln Summary: In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact…

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Energy-dependent epigenetic translation to mRNA stability (6)

See: Energy-dependent epigenetic translation to mRNA stability (5) Five energy-dependent amino acid substitutions are linked to differences in RNA content and biodiversity in 4 mammalian species. Excerpt: Species- and tissue-specific variation in mt-tRNA incorporation into the mt-LSU was analyzed….  Analysis of porcine dermal fibroblasts (C), human osteosarcoma 143B cells (D), bovine cardiac tissue (E), and rat hepatic tissue (F) depicts the relative abundance of each mt-tRNA across fractions (ImageQuant software); represented as a percentage of the total signal. In my…

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Energy-dependent epigenetic translation to mRNA stability

Negative selection in humans and fruit flies involves synergistic epistasis Negative selection against deleterious alleles produced by mutation influences within-population variation as the most pervasive form of natural selection. Naturally occurring positive selection for energy-dependent codon optimality replaced every aspect of neo-Darwinian theories that linked natural selection from mutations to evolution of increasing organismal complexity. Positive selection for epigenetically-effected beneficial alleles links the epigenetic landscape to the physical landscape of supercoiled DNA via nutrient-dependent pheromone-controlled metabolic networks and genetic networks.…

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Energy as information and constrained endogenous RNA interference (4)

Premise: Sunlight is the energy as information that is required to link endogenous RNA interference to healthy longevity Counter claim:  The Quantum Thermodynamics Revolution: Information theory Understanding entropy as a subjective measure allows the universe as a whole to evolve without ever losing information. Precision Medicine virtual conference, Feburary 22-23, 2017 Title: Energy as information and constrained endogenous RNA interference  James V. Kohl RNA-mediated.com jvkohl@bellsouth.net Abstract describing the poster   Narrative: The term microRNA has been used in 58,000 indexed…

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Ignoring peer review, ATP, and microRNA biosynthesis

Cell diversity and network dynamics in photosensitive human brain organoids …neuronal activity within organoids could be controlled using light stimulation of photosensitive cells, which may offer a way to probe the functionality of human neuronal circuits using physiological sensory stimuli. They are not going to tell anyone that these findings link the speed of light on contact with water to the energy-dependent physiology of reproduction in all living genera because the physiology of reproduction is nutrient-dependent and pheromone-controlled. Everyone knows…

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Cytosis: Biology Content

  Help Me Write Some Biology Content Project Update #5: Cytosis: A Cell Biology Board Game by John Coveyou (Genius Games) Many of you have mentioned that you’d like to have an explanation of the biology behind Cytosis available… and I think that is an AWESOME plan. Every time I’ve taught the game to non-science players in the past, they say gameplay made even more sense (and was so much more enjoyable) when I explained the science as well. This…

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Allen Institute confirms food energy is information

See also: Theistic evolutionists fight back and lose Excerpt: Predictably, Paul Allen will be the next to start funding works that might help to prevent the viral apocalypse, now that Bill Gates is mentally prepared to do so. Allen Institute FB page 3/3/17 Fascinating new research on stem cell division Scientists discover an unexpected influence [of food] on dividing stem cells’ fate One particular protein, Pex11b, caught her attention. It is associated with the membrane that surrounds the peroxisome, an…

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Theistic evolutionists fight back and lose (3)

See also: Theistic evolutionists fight back and lose See also: Theistic evolutionists fight back and lose (2) For succinct representations of the claims made by people who are obviously biologically uninformed, see: 7/25/13 Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian…

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