schizophrenia

Electron cloud superimposed on the yin yang symbol

The “walking fish” walks straight from quantum physics to quantum souls (3)

The molecular dynamics of the hydrophobic amino acid, valine, link the anti-entropic virucidal energy of sunlight from the Second Law of Thermodynamics to the energy-dependent and temperature-dependent orientational dynamics of the structure of water via methylation and acetylation in the C and N terminus, respectively. The quantized energy of sunlight must be linked from energy as information to energy-dependent methylation and acetylation to all biodiversity via the effect of the energy on contact with water and the physiology of pheromone-controlled…

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Trashing the 2nd Law

Summary: Autophagy is the antiphage defense strategy. (December 8, 2016) Other definitions no longer apply. See: Experiment shows that arrow of time is a relative concept, not an absolute one Everything that theorists were taught to believe about entropy was probably based on the ridiculous assumption that “…there are no correlations between particles.” Everything known to serious scientists about energy-dependent autophagy shows that the creation of energy must be linked from the biophysically constrained physiology of pheromone-controlled reproduction via feedback…

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Mouse morphs and primate diversity in 50 years

Excerpt: Analysis of the crystal structure of deer mouse Hb at 1.8 Å resolution (24, 25) revealed that each of the eight rHb mutants is characterized by a unique constellation of hydrogen bonds within and between subunits (Table 2 and fig. S2). Additional hydrogen bonds between subunits of the same αβ dimer are formed in the presence of β128Ser (an L-type residue; fig. S2), which contributes to the observed epistasis between allelic α- and β-chain variants. ——————————— Energy-dependent RNA-mediated biophysically…

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Inventing “Transcriptome Trajectory Turning Points”

Summary: They invented the term “Transcriptome Trajectory Turning Points” to prevent others from learning that virus-driven energy theft is the cause of all pathology. Scientists discover genetic timetable of brain’s aging process The biggest reorganisation of genes occurs during young adulthood, peaking around age 26, the team found. These changes affected the same genes that are associated with schizophrenia. The team says this could explain why people with schizophrenia do not show symptoms until young adulthood, even though the genetic…

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Energy-dependent physical and biophysical constraints (2)

Summary: The mind does not exist in nature. It is a manifestation of how ecological variation must be linked to the creation of food energy-dependent pheromone-controlled ecological adaptations. Energy-dependent physical and biophysical constraints (1) The energy-dependent de novo creation of all receptors is biophysically constrained. See: Channel opening and gating mechanism in AMPA-subtype glutamate receptors This was reported as: Scientists capture first image of major brain receptor in action Defects in glutamate receptors, or the processes they mediate, are implicated…

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Hydrogen-atom energy in DNA base pairs

See also: Consciousness is simply food rearranged Role of Double Hydrogen Atom Transfer Reactions in Atmospheric Chemistry Abstract excerpt:  Hydrogen atom transfer (HAT) reactions are ubiquitous and play a crucial role in chemistries occurring in the atmosphere, biology, and industry. My comment: The link from physics to chemistry and the conserved molecular mechanisms of biologically-based RNA-mediated cell type differentiation has been the focus my works for more than 20 years, even before I knew what I would need to explain…

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Linking RNA structure to function

A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage was reported on September 8, 2016 as: Linking RNA structure and function Excerpt 1) Learning more about how lncRNAs control cell differentiation could offer a new approach to developing drugs for patients whose hearts have been damaged by cardiovascular disease, aging, or cancer. The insult to the intelligence of all serious scientists who have linked energy-dependent changes from angstroms to ecosystems in…

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Nutrient-dependent life vs virus-driven pathology

Young Earth Creationists killing Christian credibility? Perry Marshall says: March 19, 2016 at 10:04 am James, you are one step away from being banned because of your disingenuous comments, your accusations, and your unnecessary combativeness. I am getting tired of it. People accuse you of being a troll for a reason. This is your final warning. My comment: Thanks for the warning, Perry Marshall. People who do not like me to disseminate accurate information about biologically-based cause and effect accuse…

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RNA-mediated events and "The Theory of Everything"

The Large Scale Structure of Space-Time Co-author George F.R. Ellis won the 2004 Templeton Prize People like him are likely to recognize the top-down link from light-induced de novo creation of nucleic acids and nutrient-dependendent RNA-mediated amino acid substitutions to epigenetically-effected neuronal structure and function. In my model, light-induced amino acid substitutions are linked to the nutrient-dependent amino acid substitutions that differentiate all cell types of all individuals of all organisms. Neuronal cell type differentiation is linked to behavior. See…

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More than a bag of chemicals?

From Fertilization to Adult Sexual Behavior (1996) Excerpt: “Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans…” My comment: How far can this model of RNA-mediated cell type differentiation go? What links the model to ADHD? Could it be a single amino acid substitution (see below)? If so, can the response to ADHD pharmacotherapy be predicted by what is…

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