SNPs

Sexual communication signals: New Insights!

Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull New insights in the evolution of sexual communication signals Abstract excerpt: Our research focuses on identifying a) the genes underlying sexual signals and responses in both sexes2-4, and b) ecological factors that may cause divergence in…

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Energy-dependent pheromone-controlled entropy (2)

See also: Energy-dependent pheromone-controlled entropy (1) Let’s make peer review scientific …peer review is often biased and inefficient. It is occasionally corrupt, sometimes a charade, an open temptation to plagiarists. Even with the best of intentions, how and whether peer review identifies high-quality science is unknown. It is, in short, unscientific. The androgynous baby-faced boy or girl pictured among those wearing pink “crotch” hats appears to representing others at the March for Women. The sign may also be representing the…

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Bill Gates refutes theistic evolution (sequel)

See: Bill Gates refutes theistic evolution See also: Gate-controlled conductance switching in DNA Conclusion: Our work demonstrates one can introduce an active control to DNA conductance by modifying a base with a redox group, and switch the DNA conductance reversibly between two levels by oxidizing or reducing the redox group with an EC gate. This strategy could be implemented in more sophisticated DNA nanostructures for active device building blocks. As the DNA conductance is an indicator of the molecule in…

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Bill Gates refutes theistic evolution

See: Bill Gates refutes theistic evolution (prequel) See for comparison: Our 2017 Annual Letter Warren Buffett’s Best Investment By Bill and Melinda Gates | February 14, 2017 Malnourished children can be getting enough calories, but not the right nutrients. That makes them more susceptible to conditions like pneumonia or diarrhea—and more likely to die from them. If malnourished children are not getting the right nutrients, they focused too much on vaccines and not enough on what is known about nutritional…

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Phylogenetic similarity sans energy

Phylogenetic Similarity of Popular Rice Varieties from Different Sources (2016) Cites: Sablok and Shekhawat (2008) Excerpt: “Microsatellites, often abbreviated as simple sequence repeats (SSRs), are 1 to 5 bp repeat mutation prone motifs. Due to mutation prone specific and high rate of polymorphism, microsatellites (SSR) have become a modern genetic resource tool for the genetic mapping studies, developing and establishing new patterns of molecular breeding and in inferring the phylogenetic and comparative genome analysis. These repetitive stretches are distributed in…

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Light, behavior and autophagy, a gender-specific risk factor

Structure of photosystem II and substrate binding at room temperature Excerpt: PS II, a membrane-bound multi-subunit pigment protein complex, couples the one-electron photochemistry at the reaction centre with the four-electron redox chemistry of water oxidation at the Mn4CaO5 cluster in the oxygen-evolving complex (OEC). New, detailed snapshots capture photosynthesis at room temperature The living machinery responsible for photosynthesis – while commonplace and essential to life on Earth – is still not fully understood. It is understood at every level of…

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Controlled amino acid treatment of all pathology

Amino acid studies.com Excerpt: One of the cancer treatments that seems to be proving effective over time is CAAT: Controlled Amino Acid Treatment. CAAT works by restricting certain amino acids from the diet to combat the growth and reproduction of the cancerous cells. Excerpt: doctors can now actively battle cancers, using the best weapons possible, natural amino acids, which are actually designed to make changes in the body. The trick has been to understand which changes are beneficial to cancer…

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Energy-dependent purifying selection / autophagy (3)

See also: Energy-dependent purifying selection / autophagy (2) But see: Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters Re: “…the interactomes of 31,253 annotated promoters in 17 human primary blood cell types.” Excerpt: Here, we link thousands of GWAS SNPs to their putative target genes and prioritize more than 2,500 potential disease-associated genes, three-quarters of which were not previously implicated. Reported as: Researchers identify missing links that connect human DNA variation with disease My comment:…

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Base pairs, amino acids and phenotypes

Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase DNA repair by homologous recombination (HR) underpins cell survival and fuels genome instability, cancer, and evolution. Autophagy is the established link from energy-dependent changes in base pairs and RNA-mediated amino acid substitutions to DNA repair in the context of polycombic ecological adaptations that prevent the hecatombic evolution of virus-driven pathology. Inventing new detailed models of DNA repair serves only to confuse those who have already…

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Rs3827760 is Val370Ala and EDARV370A

Introduction: A Single Nucleotide Polymorphism (SNP) is a DNA sequence variation in which a single nucleotide — A, T, C or G — in the genome (or other shared sequence) differs between members of a biological species or paired chromosomes. SNPs within a coding sequence do not necessarily change the amino acid sequence of the protein that is produced. Rs3827760 is Val370Ala Excerpt: …Val370Ala, is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2. The EDAR gene…

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