speciation

Light-controlled cell biology (revisited)

See Sci-Bay Scholar for citations and downloads of more than 3300 published works that link viruses to microRNAs Summary: …either the organized genomes of all cell types use the energy source, or viruses use the biophysically constrained energy of the cell types. No extant species can be used as an example of how the virus-driven theft of quantized energy can be linked from natural selection to the evolution of a new species. See also, with my emphasis: Light Offers New…

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Denying Creation via RNA-directed DNA methylation

Summary: Epigenetic mechanisms did not evolve.  DNA methylation is food energy-dependent and RNA-directed. Phenotypes are not fixed by genetics. The food energy-dependent RNA-directed DNA methylation of all organized genomes is biophysically constrained by the metabolism of food to pheromones, which control the physiology of food-dependent reproduction. On the day after he posted content on the refutation of Karl Popper’s nonsense and the pseudoscientific nonsense touted in every aspect of neo-Darwinian theory, antagonist Jay Feierman posted this to the Human Ethology…

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Viruses in pathogenic variants disrupt alternative splicings

Pathogenic variants that alter protein code often disrupt splicing Approximately 10% of exonic mutations altered splicing, mostly by disrupting multiple stages of spliceosome assembly. We present a large-scale characterization of exonic splicing mutations using a new technology that facilitates variant classification and keeps pace with variant discovery. Assay of nearly 5,000 mutations reveals roots of genetic splicing errors “Splicing errors can be very deleterious because instead of just changing one amino acid [the building block of a protein], it can…

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Survivors of RNA-mediated terrorism

In Darwin’s Radio and Darwin’s Children, Greg Bear predicted there would be ecologically adapted survivors of the forthcoming viral apocalypse.  Could his “raw insight” help to save you, or help to save any of your loved ones who are not already dead? Or, is it too late for us all? See: “The Darwin Code: Intelligent Design without God” Excerpt:  Once again, evolution is a fresh territory, much larger than anyone thought. The Darwin code–the key to all of our new…

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Science vs semantics

Re-interpreting long-term evolution experiments — Is delayed adaptation an example of historical contingency or a consequence of intermittent selection? Excerpt: “… the series of events used to explain adaptation in the short-transfer LTEE (and in speciation) might need to be revised. The amplification model supported by this article has already be proposed as a means of evolving new genes (1) and has been experimentally shown capable of generating a novel genetic function within as few as 3000 cell generations (11).…

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Teleophobes vs teleophiles: a recent history

  Teleology is a reason or explanation for something in function of its end, purpose, or goal. The teleological or physico-theological argument, also known as the argument from design, or intelligent design argument is an argument for the existence of God or, more generally, for an intelligent creator “based on perceived evidence of deliberate design in the natural or physical world” My comment: Teleophobes make weak arguments peppered with logical fallacies.  They do not make physico-theological arguments, which can be supported…

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RNA-mediated theory killers

Brain-manipulation studies may produce spurious links to behaviour Study shows that controlling neurons with light or drugs may affect the brain in more ways than expected. Excerpt: Given that many experiments build on existing knowledge about circuits involved in a behaviour, he cautions, experimental scientists should be particularly careful when using transient techniques to map entirely new circuits in the brain. “This study nicely reminds us that there is no perfect technique,” says Evan Feinberg, a neuroscientist at the University…

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Theorists: No rational thinking allowed

A User’s Guide to Rational Thinking Excerpt: When geneticists offer contrary ideas about how speciation occurs, they’re debating the nuts and bolts of how evolution works, not arguing over whether it happens. My comment: When serious scientists explain how speciation occurs, they integrate what is known about the biophysically constrained chemistry of nutrient-dependent RNA-mediated protein folding. They include experimental evidence that shows amino acid substitutions link the epigenetic landscape to the physical landscape of DNA in the organized genomes of…

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Jumping back: Science or Pseudoscience?

Daily Comment November 21, 2014 European Science’s Great Leap Backward By Michael Specter Excerpt 1) “When politicians reject verifiable data and reputable research and rely instead on politics or desire, the results can be devastating.” Excerpt 2 with my emphasis) “…scientific organizations from around the world… have strongly endorsed the safety of G.M. foods. (It should be noted that the U.S. can claim no superiority in our approach to evidence-based science, as demonstrated by the fact that nearly half of…

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RNA-mediated events and "The Theory of Everything"

The Large Scale Structure of Space-Time Co-author George F.R. Ellis won the 2004 Templeton Prize People like him are likely to recognize the top-down link from light-induced de novo creation of nucleic acids and nutrient-dependendent RNA-mediated amino acid substitutions to epigenetically-effected neuronal structure and function. In my model, light-induced amino acid substitutions are linked to the nutrient-dependent amino acid substitutions that differentiate all cell types of all individuals of all organisms. Neuronal cell type differentiation is linked to behavior. See…

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