species

Polymaths and paradigm shifts: from Asimov to Bear (2)

Polymaths and paradigm shifts: from Asimov to Bear (1) See also: Search results for virus-driven energy theft Summary: The creation of enzymes, such as ATP synthase is energy-dependent. The energy biophysically constrains viral latency via the creation of microRNAs and RNA-mediated amino acid substitutions that differentiate the cell types of all living genera. Modifying Other’s Originality without Quote is an Act of Piracy A writer who does not cite the sources in h/h feature article is committing piracy. Piracy is…

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An evolutionary theory killer

Subatomic: From thermophiles to humans (2)

Summary: As more information about natural selection for energy-dependent codon optimality made it clear that food energy was essential for species survival, the theorists continued to refuse to use experimental evidence to support their claims about how mutations and natural selection could lead to the evolution of a new species. Now, the theorists are left with foolish claims, like this “…the universe simply is, without ultimate cause or explanation.” Why Is There Something, Rather Than Nothing? by Sean M. Carroll…

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MicroRNAs and the Cassandra syndrome (revisited)

Conclusion: Serious scientists can explain every aspect of energy-dependent biophysically constrained viral latency in the context of details about these pathways and everything that links changes from electrons to ecosystems in all living genera. Why are the serious scientists still challenged by “…the tendency of academia to reject any academic-like work from outside academia?” What aspect of the academic contribution that could lead to the cure for all pathology do biologically uninformed academics want to continue to reject and attack?…

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Energy-dependent purifying selection / autophagy

This is a multi-part series. See also: Energy-dependent purifying selection / autophagy (2-6) Pain from Cells that Are Not Neurons Introduction: Recent research on pain shows a very surprising result. A new type of neuroplasticity has been discovered… My comment: It’s discovery does not make it a new type of neuroplasticity. Discoveries like this attest only to the ignorance of theorists who have never considered the role that virus-driven energy theft plays in all pathology. Excerpt 1) Injuries produce ATP…

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The tipping point? 50, 000 publications (2)

Pubmed.com “microRNA” Hedgehog signaling enables nutrition-responsive inhibition of an alternative morph in a polyphenic beetle Excerpt: Significance Complex, nongradual responses to environmental conditions are commonplace in nature and perhaps most extreme in polyphenic insects where continuous variation in nutrition experienced in early development gives rise to discrete alternative castes or morphs. This research shows that the hedgehog (Hh) pathway has acquired a novel and highly unusual role in the nutrition-dependent regulation of polyphenic development of a beetle. Experimental repression of…

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The radical pair mechanism of ecological speciation

The radical pair mechanism and the avian chemical compass: Quantum coherence and entanglement Excerpt: Radical pairs are usually produced as short-lived intermediates through decomposition, electron transfer, or hydrogen transfer reactions from singlet or triplet excited states. My comment: The radical pair mechanism appears to be another link from nutrient energy-dependent hydrogen-atom transfer in DNA base pairs to ecological speciation. However, the hydrogen-atom transfer in DNA base pairs mechanism seems to have gone unrecognized despite this report. Induction of micronuclei and superoxide production…

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Thermotolerance and Longevity

Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity Excerpt: …it was hypothesized that hsf-1 regulates the aging process by modulating chaperone network components to directly influence the folding state of the proteome ( Morimoto, 2008). Our data suggest an alternate method by which hsf-1 can regulate the aging process. In this model, hsf-1 activates the FOXO transcription factor, which initiates a pro-longevity stress response that is distinct from the heat shock response. My comment: The separation of the nutrient…

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Theoretical physics and molecular biology

Astrophysical phenomenology meets pheromone-ology: Slugs that “eat light” Theoretical physics and molecular biology can be compared in the context of their explanatory power. For example (with my emphasis): Theoretical physics (2015): Firewall Phenomenology with Astrophysical Neutrinos Abstract: One of the most fundamental features of a black hole in general relativity is its event horizon: a boundary from which nothing can escape. There has been a recent surge of interest in the nature of these event horizons and their local neighbourhoods.…

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Unified nutritional and molecular mechanisms

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits Article image: Excerpt: “…unifying nutritional and molecular mechanisms remain elusive.” Reported as Molecular mechanism behind health benefits of dietary restriction identified Excerpt 1) “Dietary restriction is a type of intervention that can include reduced overall food intake, decreased consumption of particular macronutrients such as protein, or intermittent bouts of fasting. It is known to have beneficial health effects, including protection from tissue injury and improved metabolism. It has also been…

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Extensive molecular evidence vs ridiculous theories

Mosquito Genomes Galore Whole-genome sequences of 16 different mosquito species reveal rapid evolution and could inform malaria research. By Ruth Williams | November 27, 2014 Excerpt: “…mosquitoes are rapidly evolving, exhibiting high degrees of gene gains, losses, shuffling, and even transmission between closely related species.” It is the reports on rapid evolution of insects that continues to limit the usefulness of any theories about mutations and or natural selection of anything except food. My comments (below) to The Scientist site…

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