synthesis of RNA

Polymaths and paradigm shifts: from Asimov to Bear (4)

Saying Goodbye to the RNA World Theory RNA has a limited ability for catalysis compared to peptides, and would have struggled to maintain its catalytic activity under the changing temperature conditions of early Earth. Carter and Wills also argued that if an RNA world existed, it would have been unlikely for it to incorporate peptides later on. See for comparison: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)…

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An evolutionary theory killer

A reversible TCA cycle in a thermophile

Make no mistake, pseudoscientists have stolen the soul of science for more than 20 years, with their ridiculous claims about mutations and evolution. For comparison, see: “…considering that we have just 3 such round Nos ‘100’ ‘1000’ ‘10000’, its just three out of all realistic possibilities, no? Admit its looks cool just bec. we calc in Dec system. History books claims was invented by ancient societies; but I think its evolution: We have 10 fingers!” My reply (SARCASM ALERT): Thanks.…

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The tipping point (revisted): 69,000 publications

See first: The tipping point (revisited): 68,000 publications December 21, 2017 On December 24, 2017, I started a “tweet” series on Twitter, which was designed to test the response to accurate information about RNA-mediated energy-dependent biophysically constrained viral latency. Nearly 80,000 impressions have led to few engagements and virtually no discussion during a time when almost 1000 additional published works have been indexed on the PubMed database. In my January 20, 2018 PubMed search for term “microRNA,” among nearly 69,000 results,…

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Interethnic genetic similarities and differences (2)

From Massivesci.com Simulating evolution helped scientists design a better virus: It sounds like an arcane superpower. It boils down to random mutation and selection  January 9, 2018 See also: In an information ecosystem that grows ever more politically siloed, such lines of study are worth pursuing. January 11, 2018 Information ecosystems are energy-dependent. See: MicroRNA + cadherin The creation of adhesion proteins prevents genomic entropy. On January 11, 2018 Nadja (Chief Content Officer) from Massivesci.com wrote: We’re in the midst…

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From base editing to RNA editing (7)

Group Description Human ethology is the study of the biology of human behavior, including the behavior’s phylogeny (evolutionary history), ontogeny (development), proximate causes, and adaptiveness (survival value). Jay R. Feierman wrote: This has nothing to do with human ethology. So, I can’t publish it to the group. This is what he refused to publish to the group: ———— Two generations of serious scientists have already been taught to make claims like this (although some must be forced to do it):…

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Predicting who wins the 2017 Nobel Prizes (7)

Conclusion: The biggest threat to humanity is not the “Big Bang” theory of creation or the “Big Bang” theory of how life on Earth might end after an explosion of cosmic proportions. The biggest threat has always been “human idiocy.” 2017 Nobel Peace Prize Awarded to International Campaign to Abolish Nuclear Weapons “for its work to draw attention to the catastrophic humanitarian consequences of any use of nuclear weapons and for its ground-breaking efforts to achieve a treaty-based prohibition of…

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Host-derived creation of all pathology (2 of 2)

Summary: All serious scientists know that all epigenetic diversity is food energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction. See for comparison: Jay R. Feierman: “Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.” A Bacterial Messenger Molecule Extends Healthspan …indole,…

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Epigenetic effects of stress by Bruce McEwen (2)

Summary: …rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.   This was reported in the following context: “RNA molecules live short lives” July 12, 2017 See also: Epigenetic effects of stress by Bruce McEwen (1) Summary: In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact that RNA biosynthesis…

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Cytosis: Gameplay Runthrough

For comparison: Neo-Darwinian theorists do not start with the ATP-dependent de novo creation of RNA and/or receptors. That is probably why the theorists do not know that cell type differentiation is energy-dependent (ATP-dependent). That fact means they may also not know that virus-driven energy theft causes the degradation of messenger RNA. That fact means they cannot link mutations to all pathology. That fact means the silly theorists have not updated their knowledge base since 1964. They’ve played the “evolution” game,…

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